6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one

Base Information

• Chemical Name: 6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one
• CAS No.: 1312947-79-7
• Molecular Formula: C₃₁H₂₁N₃O₄S
• Molecular Weight: 531.591
• Mol file: 1312947-79-7.mol

Synonyms:

Chemical Property of 6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one

There total 4 articles about 6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-benzoic acid (150-13-0,159246-81-8,8014-65-1) → 6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one (1312947-79-7)

Guidance literature:

Multi-step reaction with 4 steps

1: hydrogenchloride / water / Heating

2: 2 h / Reflux

3: polyphosphoric acid / 5 h / 100 °C

4: pyridine / 6 h / Reflux

With pyridine; hydrogenchloride; In water;

DOI:10.1002/jhet.245

Reference yield:

4-(2-imino-5-oxothiazolidin-3-yl)-benzoic acid (1312947-68-4) → 6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one (1312947-79-7)

Guidance literature:

Multi-step reaction with 2 steps

1: polyphosphoric acid / 5 h / 100 °C

2: pyridine / 6 h / Reflux

With pyridine;

DOI:10.1002/jhet.245

Reference yield:

4-thioureidobenzoic acid (7366-56-5) → 6-(2-imino-5-oxothiazolidin-3-yl)-3,4-diphenyl-2-(2-carboxilic acid)-isoquinolin-1(2H)-one (1312947-79-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 2 h / Reflux

2: polyphosphoric acid / 5 h / 100 °C

3: pyridine / 6 h / Reflux

With pyridine;

DOI:10.1002/jhet.245

upstream raw materials:

4-(2-imino-5-oxothiazolidin-3-yl)-benzoic acid

2-imino-3-(-1-oxo-3,4-diphenyl-1H-isochromen-6-yl)thiazolidin-5-one

anthranilic acid

4-thioureidobenzoic acid

Refernces