O-(3,4,5-Trimethoxy-trans-cinnamoyl)fumagillol

Base Information

Chemical Name:O-(3,4,5-Trimethoxy-trans-cinnamoyl)fumagillol
CAS No.:251111-15-6
Molecular Formula:C₂₈H₃₈O₈
Molecular Weight:502.605
Hs Code.:
UNII:540N75454L
Nikkaji Number:J1.234.693J
Pharos Ligand ID:U7KBX5TJTAXL
ChEMBL ID:CHEMBL137766

Synonyms:CKD 731;CKD-731

Suppliers and Price of O-(3,4,5-Trimethoxy-trans-cinnamoyl)fumagillol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of O-(3,4,5-Trimethoxy-trans-cinnamoyl)fumagillol

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:11
Exact Mass:502.25666817
Heavy Atom Count:36
Complexity:823

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=CCC1C(O1)(C)C2C(C(CCC23CO3)OC(=O)C=CC4=CC(=C(C(=C4)OC)OC)OC)OC)C
Isomeric SMILES:CC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)/C=C/C4=CC(=C(C(=C4)OC)OC)OC)OC)C

Technology Process of O-(3,4,5-Trimethoxy-trans-cinnamoyl)fumagillol

There total 2 articles about O-(3,4,5-Trimethoxy-trans-cinnamoyl)fumagillol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 20329-98-0,20329-99-1,90-50-6
(E)-3,4,5-trimethoxy-cinnamic acid

: 35903-52-7,128656-25-7,132746-73-7,108102-51-8
fumagillol

: 251111-15-6
CDK-731

: 3-(3,4,5-trimethoxyphenyl)acrylic acid 4-chloromethyl-4-hydroxy-2-methoxy-3-[2-methyl-3-(3-methylbut-2-enyl)oxiranyl]cyclohexyl ester

Guidance literature:: (E)-3,4,5-trimethoxy-cinnamic acid; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

fumagillol; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2003.08.031