Technology Process of C19H24F3N3O5
There total 5 articles about C19H24F3N3O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: thionyl chloride / ethyl acetate / 3 h / Inert atmosphere; Reflux
1.2: 0 - 20 °C / Inert atmosphere
2.1: sodium azide; water / acetone / 1.5 h / 20 °C
2.2: 48 h / 20 °C
With
thionyl chloride; sodium azide; water;
In
ethyl acetate; acetone;
DOI:10.1021/ol500616v
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium azide; water / acetone / 1.5 h / 20 °C
1.2: 48 h / 20 °C
With
sodium azide; water;
In
acetone;
DOI:10.1021/ol500616v
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: dichloromethane / 17 h / 20 °C / Inert atmosphere
2.1: methanesulfonamide; AD-mix-α; water / tert-butyl alcohol / 96 h / 0 °C / Inert atmosphere
3.1: thionyl chloride / ethyl acetate / 3 h / Inert atmosphere; Reflux
3.2: 0 - 20 °C / Inert atmosphere
4.1: sodium azide; water / acetone / 1.5 h / 20 °C
4.2: 48 h / 20 °C
With
thionyl chloride; sodium azide; methanesulfonamide; AD-mix-α; water;
In
dichloromethane; ethyl acetate; acetone; tert-butyl alcohol;
1.1: |Wittig Olefination / 2.1: |Sharpless Dihydroxylation;
DOI:10.1021/ol500616v