Technology Process of Propanedinitrile, [2,2-bis(1-methylethyl)-4,4-diphenyl-3-butenylidene]-
There total 5 articles about Propanedinitrile, [2,2-bis(1-methylethyl)-4,4-diphenyl-3-butenylidene]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; titanium tetrachloride;
In
tetrahydrofuran; tetrachloromethane;
1.) 0 deg C, 25 min, 2a.) room temp., 5.5 h, 2b.) 43 deg C, 60 h;
DOI:10.1021/jo00277a013
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1.) LDA / 1.) THF, -78 deg C, 10 min, 2a.) -78 deg C, 2b.) room temp., 18 h
2: 1.) LDA / 1.) 1,2-dimethoxyethane, -78 deg C to 0 deg C, 30 min, 2a.) 0 deg C, 90 min, 2b.) room temp., 115 h
3: 81 percent / 1.0 M diisobutylaluminum hydride / hexane / 2 h / Ambient temperature
4: 95 percent / pyridinium chlorochromate / CH2Cl2 / 8.5 h
5: 14 percent / 1.) TiCl4, 2.) pyridine / CCl4; tetrahydrofuran / 1.) 0 deg C, 25 min, 2a.) room temp., 5.5 h, 2b.) 43 deg C, 60 h
With
pyridine; titanium tetrachloride; diisobutylaluminium hydride; pyridinium chlorochromate; lithium diisopropyl amide;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane;
DOI:10.1021/jo00277a013
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 95 percent / pyridinium chlorochromate / CH2Cl2 / 8.5 h
2: 14 percent / 1.) TiCl4, 2.) pyridine / CCl4; tetrahydrofuran / 1.) 0 deg C, 25 min, 2a.) room temp., 5.5 h, 2b.) 43 deg C, 60 h
With
pyridine; titanium tetrachloride; pyridinium chlorochromate;
In
tetrahydrofuran; tetrachloromethane; dichloromethane;
DOI:10.1021/jo00277a013