spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine>

Base Information

• Chemical Name: spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine>
• CAS No.: 24024-50-8
• Molecular Formula: C₁₆H₁₄N₂OS₂
• Molecular Weight: 314.432
• Mol file: 24024-50-8.mol

Synonyms:

Chemical Property of spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine>

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine>

There total 3 articles about spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine> which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

3-methylbenzothiazolium iodide (2786-31-4) → spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine> (24024-50-8) + 3-methyl-(3H)benzothiazolone (2786-62-1) + 3,3’-dimethyl-3H,3’H-2,2’-spirobi[1,3]benzothiazole (17823-21-1) + 11,14-dimethyldibenzo<1,2,5,8>dithiadiazecine-12,13(11H,14H)-dione (51479-83-5)

Guidance literature:

3-methylbenzothiazolium iodide; With triethylamine; In acetonitrile; at 0 - 20 ℃; for 24h;

With oxygen;

DOI:10.1002/chir.22492

Reference yield:

3-methylbenzothiazolium iodide (2786-31-4) → spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine> (24024-50-8) + 3,3’-dimethyl-3H,3’H-2,2’-spirobi[1,3]benzothiazole (17823-21-1) + 7,14-dimethyl-7H,14H-dibenzo[d,i][1,6,3,8]dithiadiazecine-6,13-dione (16407-45-7)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide;

Reference yield:

bi(3-methylbenzothiazolinylidene) (21583-22-2) → spiro-2,2'-<2',3'-dihydro-4'-methyl-3'-oxo-4'H-benzo-1',4'-thiazine> (24024-50-8) + 3,3’-dimethyl-3H,3’H-2,2’-spirobi[1,3]benzothiazole (17823-21-1) + 7,14-dimethyl-7H,14H-dibenzo[d,i][1,6,3,8]dithiadiazecine-6,13-dione (16407-45-7)

Guidance literature:

With oxygen; In acetone; Heating;

upstream raw materials:

3-methylbenzothiazolium iodide

bi(3-methylbenzothiazolinylidene)