(6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole

Base Information

• Chemical Name: (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole
• CAS No.: 69461-07-0
• Molecular Formula: C₃₂H₄₀N₄
• Molecular Weight: 480.696
• Mol file: 69461-07-0.mol

Synonyms:6H-Isoindolo[2,1-a]indole-11-ethanamine,6a,7,8,10a-tetrahydro-N,7,7,9-tetramethyl-6-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-,(6a,6aa,10aa)-; (?à)-Isoborreverine; Isoborreverine

Chemical Property of (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole

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Technology Process of (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole

There total 10 articles about (6R)-6aβ,7,8,10aβ-Tetrahydro-7,7,9-trimethyl-11-[2-(methylamino)ethyl]-6β-[3-[2-(methylamino)ethyl]-1H-indol-2-yl]-6H-isoindolo[2,1-a]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

(+/-)-Borrerine (51076-19-8,119945-42-5) → Isoborreverin (69437-61-2,69461-07-0)

Guidance literature:

With trifluoroacetic acid; at 65 ℃; for 48h; neat (no solvent);

DOI:10.1021/ja301387k

Reference yield:

(+/-)-Borrerine (51076-19-8,119945-42-5) → flinderole A + des-methylflinderol C + Isoborreverin (69437-61-2,69461-07-0)

Guidance literature:

With trifluoroacetic acid; In benzene; at 55 ℃; for 1.33333h; Temperature; Time; Solvent; Reagent/catalyst;

Reference yield:

(+/-)-Borrerine (51076-19-8,119945-42-5) → flinderole A + desmethylflinderole C + Isoborreverin (69437-61-2,69461-07-0)

Guidance literature:

With trifluoroacetic acid; In benzene; at 65 ℃; for 0.5h;

DOI:10.1021/ja301387k

upstream raw materials:

tryptamine

methyl 1-(2-methylprop-1-enyl)-3,4-dihydro-1H-pyrido[3,4-b]indole-2(9H)-carboxylate

(+/-)-Borrerine

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