1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat

Base Information

• Chemical Name: 1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat
• CAS No.: 58992-26-0
• Molecular Formula: BF₄*C₂₇H₂₄PS
• Molecular Weight: 498.332
• Mol file: 58992-26-0.mol

Synonyms:

Chemical Property of 1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat

There total 1 articles about 1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(phenylthio)succinimide (14204-24-1) + triphenylphosphonium cyclopropylide (14633-95-5,7666-30-0) → 1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat (58992-26-0)

Guidance literature:

With lithium tetrafluoroborate; In tetrahydrofuran; at -30 ℃; for 1h; Yield given;

DOI:10.1021/jo00322a017

Reference yield:

1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat (58992-26-0) → (1S,8R,9R)-8-Iodo-9-methyl-4-phenylsulfanyl-10-oxa-tricyclo[7.2.1.01,5]dodec-4-en-11-one (76757-79-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 1.) KH / 1.) THF, room temp., 10 min, 2.) reflux, 3 d

2: 90 percent / 10percent aq. NaOH / 20 h / Heating

3: 93 percent / I₂/KI, NaHCO₃ / H₂O / 20 h

With sodium hydroxide; iodine; potassium hydride; sodium hydrogencarbonate; potassium iodide; In water;

DOI:10.1021/jo00322a017

Reference yield:

1-Phenylthiocyclopropyltriphenylphosphonium-tetrafluoroborat (58992-26-0) → 5-Methyl-1-phenylsulfanyl-2,4,7,8-tetrahydro-3H-azulene-3a-carboxylic acid (76757-75-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) KH / 1.) THF, room temp., 10 min, 2.) reflux, 3 d

2: 90 percent / 10percent aq. NaOH / 20 h / Heating

With sodium hydroxide; potassium hydride;

DOI:10.1021/jo00322a017

upstream raw materials:

N-(phenylthio)succinimide

triphenylphosphonium cyclopropylide

Downstream raw materials:

1,2,5,6-Tetrahydro-7-phenylthio-3H-pyrrolizin-3-on

(+/-)-2-(2,3,5,6,7,8-Hexahydro-5-oxo-1-phenylthio-6-indolizinyl)-1H-isoindol-1,3(2H)-dion

5-Methyl-1-phenylsulfanyl-2,4,7,8-tetrahydro-3H-azulene-3a-carboxylic acid methyl ester

5-Methyl-1-phenylsulfanyl-2,4,7,8-tetrahydro-3H-azulene-3a-carboxylic acid