(+)-tert-butyl 3-methyl-2-propylaminocarbonyloxybutanoate

Base Information

• Chemical Name: (+)-tert-butyl 3-methyl-2-propylaminocarbonyloxybutanoate
• CAS No.: 1349685-20-6
• Molecular Formula: C₁₃H₂₅NO₄
• Molecular Weight: 259.346
• Mol file: 1349685-20-6.mol

Synonyms:

Chemical Property of (+)-tert-butyl 3-methyl-2-propylaminocarbonyloxybutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-tert-butyl 3-methyl-2-propylaminocarbonyloxybutanoate

There total 1 articles about (+)-tert-butyl 3-methyl-2-propylaminocarbonyloxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Propyl isocyanate (110-78-1) + α-hydroxy-isovaleric acid t-butyl ester (2528-17-8) → (-)-tert-butyl 3-methyl-2-propylaminocarbonyloxybutanoate + (+)-tert-butyl 3-methyl-2-propylaminocarbonyloxybutanoate (1349685-20-6) + (-)-tert-butyl 2-hydroxy-3-methylbutanoate (4216-96-0) + L-α-hydroxyisovaleric acid t-butyl ester (3519-30-0)

Guidance literature:

α-hydroxy-isovaleric acid t-butyl ester; With [Cu((S,S)-((CH₃)3CCHCH₂OCN)2C(CH₃)2)](CF₃SO₃)2; In dichloromethane; at 0 ℃; for 0.166667h; Inert atmosphere;

Propyl isocyanate; In dichloromethane; at 0 ℃; for 1h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/jo201940w

upstream raw materials:

Propyl isocyanate

α-hydroxy-isovaleric acid t-butyl ester