C₆₀H₆₂N₆O₁₀

Base Information

• Chemical Name: C₆₀H₆₂N₆O₁₀
• CAS No.: 1378236-21-5
• Molecular Formula: C₆₀H₆₂N₆O₁₀
• Molecular Weight: 1027.19
• Mol file: 1378236-21-5.mol

Synonyms:

Chemical Property of C₆₀H₆₂N₆O₁₀

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₀H₆₂N₆O₁₀

There total 7 articles about C₆₀H₆₂N₆O₁₀ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

2,3,6-tri-O-benzyl-4-O-propargyl-β-D-galactosylazide (1378236-20-4) → C60H62N6O10 (1378236-21-5) + C90H93N9O15 (1378236-22-6)

Guidance literature:

at 20 ℃; for 360h; regiospecific reaction;

DOI:10.1002/anie.201201023

Reference yield:

2,3,6-tri-O-benzyl-β-D-galactopyranosyl azide (204510-90-7) → C60H62N6O10 (1378236-21-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / -15 °C

1.2: 2 h / -15 °C

2.1: 360 h / 20 °C

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1002/anie.201201023

Reference yield:

(2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-azidotetrahydro-2H-pyran-3,4,5-triyl triacetate (13992-26-2) → C60H62N6O10 (1378236-21-5)

Guidance literature:

Multi-step reaction with 6 steps

1.1: methanol; sodium methylate / 20 °C

2.1: toluene-4-sulfonic acid / acetonitrile / 24 h / 20 °C / Inert atmosphere

3.1: sodium hydride / N,N-dimethyl-formamide / 3 h / 0 - 20 °C

4.1: triethylsilane; trifluoroacetic acid; trifluoroacetic anhydride / dichloromethane / 5 h / 0 - 20 °C

5.1: sodium hydride / N,N-dimethyl-formamide / 0.17 h / -15 °C

5.2: 2 h / -15 °C

6.1: 360 h / 20 °C

With methanol; triethylsilane; sodium methylate; sodium hydride; toluene-4-sulfonic acid; trifluoroacetic acid; trifluoroacetic anhydride; In dichloromethane; N,N-dimethyl-formamide; acetonitrile;

DOI:10.1002/anie.201201023

upstream raw materials:

2,3,6-tri-O-benzyl-4-O-propargyl-β-D-galactosylazide

1-amido-1-deoxygalactopyranose

2,3,6-tri-O-benzyl-β-D-galactopyranosyl azide

(2R,3S,4S,5R,6R)-2-(acetoxymethyl)-6-azidotetrahydro-2H-pyran-3,4,5-triyl triacetate