2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-, (2E)-

Base Information

Chemical Name:2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-, (2E)-
CAS No.:122520-81-4
Molecular Formula:C₁₀H₈N₂O₂
Molecular Weight:188.186
Hs Code.:
DSSTox Substance ID:DTXSID40297775
Mol file:122520-81-4.mol

Synonyms:2-cyano-3-(4-hydroxyphenyl)acrylamide;2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-, (2E)-;2-cyano-3-(4-hydroxyphenyl)prop-2-enamide;122520-81-4;DTXSID40297775;CHEBI:170025;NCI60_000429;NCI60_012683

Suppliers and Price of 2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-, (2E)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-, (2E)-

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:188.058577502
Heavy Atom Count:14
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=C(C#N)C(=O)N)O

Technology Process of 2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-, (2E)-

There total 3 articles about 2-Propenamide, 2-cyano-3-(4-hydroxyphenyl)-, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 107-91-5
cyanoacetic acid amide

: 122520-81-4,3695-89-4
ST 494

Guidance literature:: With triethylamine; at 20 ℃; for 24h;
DOI:10.1016/S0040-4020(03)00554-4

Reference yield: 75.0%

: 3785-90-8
2-(4-hydroxyphenylmethylene)malononitrile

: 122520-81-4,3695-89-4
ST 494

Guidance literature:: With manganese(IV) oxide; 4-chlorobenzaldoxime; In dichloromethane; at 20 ℃; for 4h; regiospecific reaction;

Reference yield: 64.0%

: 123-08-0,65581-83-1
4-hydroxy-benzaldehyde

: 109-77-3
malononitrile

: 122520-81-4,3695-89-4
ST 494

Guidance literature:: With trifluorormethanesulfonic acid; In 1,2-dichloro-ethane; at 110 ℃; for 24h; stereoselective reaction;
DOI:10.1039/c7nj05169g