Methyl[(Z)-styryl] sulfone

Base Information

• Chemical Name: Methyl[(Z)-styryl] sulfone
• CAS No.: 37630-43-6
• Molecular Formula: C9H10 O2 S
• Molecular Weight: 182.243
• Hs Code.: 2904100000
• NSC Number: 140249
• Nikkaji Number: J2.445.302B
• Mol file: 37630-43-6.mol

Synonyms:37630-43-6;Methyl[(Z)-styryl] sulfone;SCHEMBL12324763;NSC140249;NSC-140249

Chemical Property of Methyl[(Z)-styryl] sulfone

Chemical Property:

• Vapor Pressure: 2.71E-05mmHg at 25°C
• Boiling Point: 368.4°Cat760mmHg
• Flash Point: 227.7°C
• PSA: 42.52000
• Density: 1.203g/cm³
• LogP: 2.78270
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 182.04015073
• Heavy Atom Count: 12
• Complexity: 240

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)C=CC1=CC=CC=C1
• Isomeric SMILES: CS(=O)(=O)/C=C\C1=CC=CC=C1

Technology Process of Methyl[(Z)-styryl] sulfone

There total 11 articles about Methyl[(Z)-styryl] sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-methyl(styryl)sulfane (35822-50-5) → (Z)-1-(methylsulfonyl)-2-phenylethene (37630-43-6)

Guidance literature:

With dihydrogen peroxide; acetic acid;

DOI:10.1021/ja01593a029

Reference yield:

phenylacetylene (536-74-3) → (Z)-1-(methylsulfonyl)-2-phenylethene (37630-43-6)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methanethiolate; ethanol

2: aqueous H₂O₂; acetic acid

With ethanol; dihydrogen peroxide; acetic acid; sodium thiomethoxide;

DOI:10.1021/ja01593a029

Reference yield:

((Z)-1-Methanesulfonyl-2-phenyl-vinyl)-trimethyl-silane (185844-50-2) → (E)-methyl styryl sulfone (15436-11-0) + (Z)-1-(methylsulfonyl)-2-phenylethene (37630-43-6)

Guidance literature:

With cesium fluoride; In dimethyl sulfoxide; at 40 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1039/P19960002803

upstream raw materials:

(Z)-methyl(styryl)sulfane

(E)-methyl styryl sulfone

((Z)-1-Methanesulfonyl-2-phenyl-vinyl)-trimethyl-silane

(phenylacetyl)trimethylsilane

Downstream raw materials:

(2R*,αR*)-trans-pyrrolidin-1-yl-2-<α-(methylsulphonyl)-β-phenylethyl>-4-t-butylcyclohex-6-ene

(E)-methyl styryl sulfone

methyl (α-ethoxy-β-phenylethyl)sulphone

(2R^*,αR^*)-cis-4-t-butyl-2-(α-phenyl-β-methylsulphonylethyl)cyclohexanone

Refernces

• 1、 Oishi, Shigeki,Hatano, Keisuke,Tsubouchi, Akira,Takeda, Takeshi. "Regio- and stereoselective synthesis of 1,4-dienes". body text. p. 11639 - 11640. Retrieved 2011/12/02.
• 2、 Tiecco, Marcello,Testaferri, Lorenzo,Tingoli, Marco,Chianelli, Donatella,Montanucci, Manuela. "Nucleophilic Substitutions of Unactivated Vinyl Halides with Alkanethiolate Anions in Hexamethylphophoramide". . p. 4795 - 4800. Retrieved 2007/10/02.