trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

Base Information

Chemical Name:trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene
CAS No.:145315-81-7
Molecular Formula:C₂₉H₄₈O₄Si₂
Molecular Weight:516.869
Hs Code.:

trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

Synonyms:

Suppliers and Price of trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

There total 3 articles about trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 145315-80-6
trans-1,2,3,4,4a,5,6,7,8,8aα-decahydro-1α-<(dimethylphenylsilyl)methyl>-4aβ-<(methyloxy)carbonyl>-6,6-(ethylenedioxy)-2(1H)-naphthalenone

: 145315-81-7
trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / NEt₃ / CH₂Cl₂ / 0 °C

2: LiAlH₄ / tetrahydrofuran / 8 h / 0 deg C to RT

3: 1) NaH, KH / 1) THF, 0 deg C, 10 min, 2) RT, 3 h

With lithium aluminium tetrahydride; potassium hydride; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00052a068

Reference yield:

: 145315-73-7
2,3,4,4a,5,6,7,8-octahydro-1-<(dimethylphenylsilyl)methyl>-4a-<(methyloxy)carbonyl>-6,6-(ethylenedioxy)-2(1H)-naphthalenone

: 145315-81-7
trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / liq. NH₃, Li / tetrahydrofuran / 1) -78 deg C, 20 min, 2) -78 deg C to RT

2: 90 percent / NEt₃ / CH₂Cl₂ / 0 °C

3: LiAlH₄ / tetrahydrofuran / 8 h / 0 deg C to RT

4: 1) NaH, KH / 1) THF, 0 deg C, 10 min, 2) RT, 3 h

With lithium aluminium tetrahydride; ammonia; lithium; potassium hydride; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo00052a068

Reference yield:

: 145332-91-8
trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4aβ-<(methyloxy)carbonyl>-6,6-(ethylenedioxy)naphthalene

: 145315-81-7
trans-1,4,4a,5,6,7,8,8aα-octahydro-2-(tert-butyldimethylsiloxy)-1α-<(dimethylphenylsilyl)methyl>-4αβ-<(methyloxy)methyl>-6,6-(ethylenedioxy)naphthalene

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / tetrahydrofuran / 8 h / 0 deg C to RT

2: 1) NaH, KH / 1) THF, 0 deg C, 10 min, 2) RT, 3 h

With lithium aluminium tetrahydride; potassium hydride; sodium hydride; In tetrahydrofuran;
DOI:10.1021/jo00052a068