methyl 2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate

Base Information

• Chemical Name: methyl 2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate
• CAS No.: 1246999-35-8
• Molecular Formula: C₃₆H₅₀N₄O₁₀
• Molecular Weight: 698.814
• Mol file: 1246999-35-8.mol

Synonyms:

Chemical Property of methyl 2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate

There total 1 articles about methyl 2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hex-5-ynoic acid 2,5-dioxo-pyrrolidin-1-yl ester (906564-59-8) + methyl 5-(3-aminopropyl)-2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)benzoate (1246999-41-6) → methyl 2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate (1246999-35-8)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 19h; Inert atmosphere;

DOI:10.1002/ejoc.201000546

Reference yield:

methyl 2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate (1246999-35-8) + trifluoroacetic acid (76-05-1) → methyl 2-(2-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate trifluoroacetate salt (1246999-43-8)

Guidance literature:

In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/ejoc.201000546

upstream raw materials:

hex-5-ynoic acid 2,5-dioxo-pyrrolidin-1-yl ester

methyl 5-(3-aminopropyl)-2-(2-(2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-16-yloxy)-4-hydroxyphenylazo)benzoate

Downstream raw materials:

methyl 2-(2-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)-4-hydroxyphenylazo)-5-(3-hex-5-ynamidopropyl)benzoate trifluoroacetate salt