(Z)-3-morpholinocarbonyl-3-phenylpropenoic acid

Base Information

Chemical Name:(Z)-3-morpholinocarbonyl-3-phenylpropenoic acid
CAS No.:80991-44-2
Molecular Formula:C₁₄H₁₅NO₄
Molecular Weight:261.277
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-3-morpholinocarbonyl-3-phenylpropenoic acid

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Technology Process of (Z)-3-morpholinocarbonyl-3-phenylpropenoic acid

There total 1 articles about (Z)-3-morpholinocarbonyl-3-phenylpropenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 110-91-8,99108-56-2
morpholine

: 36122-35-7
2-phenylmaleic anhydride

: 80991-44-2
(Z)-3-morpholinocarbonyl-3-phenylpropenoic acid

Guidance literature:: In benzene;
DOI:10.1039/P19810002871

Reference yield: 84.0%

: 80991-44-2
(Z)-3-morpholinocarbonyl-3-phenylpropenoic acid

: 2,5-dihydro-5-morpholiniumylidene-4-phenylfuran-2-one perchlorate

Guidance literature:: With perchloric acid; acetic anhydride; temperature did not exceed 50 deg C;
DOI:10.1039/P19810002871

Reference yield:

: 80991-44-2
(Z)-3-morpholinocarbonyl-3-phenylpropenoic acid

: 80991-45-3
(Z)-3-morpholinocarbonyl-3-phenylpropenoyl azide

Guidance literature:: Multi-step reaction with 2 steps

1: 84 percent / perchloric acid, acetyc anhydride / temperature did not exceed 50 deg C

2: 90 percent / sodium azide / H₂O; acetone

With sodium azide; perchloric acid; acetic anhydride; In water; acetone;
DOI:10.1039/P19810002871