Technology Process of C26H32FIN2O3S
There total 3 articles about C26H32FIN2O3S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / -78 °C
1.2: -78 - 20 °C
2.1: sulfuric acid; acetic acid / 20 °C
3.1: thiourea / ethanol; acetic acid / Reflux
4.1: p-toluenesulfonyl chloride; 1-methyl-1H-imidazole / acetonitrile / 0 - 20 °C
4.2: 20 °C
With
1-methyl-1H-imidazole; n-butyllithium; sulfuric acid; acetic acid; thiourea; p-toluenesulfonyl chloride;
In
tetrahydrofuran; ethanol; hexane; acetic acid; acetonitrile;
2.1: |Ritter Amidation;
DOI:10.1016/j.bmcl.2012.09.099
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: thiourea / ethanol; acetic acid / Reflux
2.1: p-toluenesulfonyl chloride; 1-methyl-1H-imidazole / acetonitrile / 0 - 20 °C
2.2: 20 °C
With
1-methyl-1H-imidazole; thiourea; p-toluenesulfonyl chloride;
In
ethanol; acetic acid; acetonitrile;
DOI:10.1016/j.bmcl.2012.09.099
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sulfuric acid; acetic acid / 20 °C
2.1: thiourea / ethanol; acetic acid / Reflux
3.1: p-toluenesulfonyl chloride; 1-methyl-1H-imidazole / acetonitrile / 0 - 20 °C
3.2: 20 °C
With
1-methyl-1H-imidazole; sulfuric acid; acetic acid; thiourea; p-toluenesulfonyl chloride;
In
ethanol; acetic acid; acetonitrile;
1.1: |Ritter Amidation;
DOI:10.1016/j.bmcl.2012.09.099
