N6-benzyl-6-azaindole

Base Information

• Chemical Name: N6-benzyl-6-azaindole
• CAS No.: 152955-67-4
• Molecular Formula: C₁₄H₁₂N₂
• Molecular Weight: 208.263
• Mol file: 152955-67-4.mol

Synonyms:

Chemical Property of N6-benzyl-6-azaindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N6-benzyl-6-azaindole

There total 6 articles about N6-benzyl-6-azaindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

6-azaindole (271-29-4) + benzyl chloride (100-44-7) → N6-benzyl-6-azaindole (152955-67-4)

Guidance literature:

In N,N-dimethyl-formamide; at 140 ℃; for 4h;

DOI:10.1016/S0040-4020(01)87211-2

Reference yield:

6-azaindole (271-29-4) + benzyl chloride (100-44-7) → N6-benzyl-6-azaindole (152955-67-4) + N1-benzyl-6-azaindole (152955-66-3)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 25 ℃; Product distribution; Rate constant; reactions with other alkylating agents; effect of var. cond.;

DOI:10.1016/S0040-4020(01)87211-2

Reference yield:

6-azaindole (271-29-4) + benzyl tosylate (1024-41-5) → N6-benzyl-6-azaindole (152955-67-4) + N1-benzyl-6-azaindole (152955-66-3)

Guidance literature:

With sodium hydride; Multistep reaction; 1.) DMF, 25-28 deg C, 45 min; 2.) DMF, 3 h, 30 deg C;

DOI:10.1016/S0040-4020(01)87211-2

upstream raw materials:

6-azaindole

benzyl tosylate

benzyl bromide

benzyl chloride

Refernces