Technology Process of (+/-)-trans-3,4-dihydroxy-syn-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene
There total 10 articles about (+/-)-trans-3,4-dihydroxy-syn-1,2-epoxy-1,2,3,4-tetrahydrodibenz[a,j]anthracene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran;
for 1h;
Ambient temperature;
DOI:10.1021/jm00402a009
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 80 percent / (KSO3)2NO, aq. KH2PO4, Adogen 464 / CH2Cl2; benzene / 1 h
2: 1.) NaBH4, O2, 2.) pyridine / 1) ethanol, room temperature, 40 h; 2) ether, THF, overnight
3: 86 percent / NaHCO3, CH3OH / tetrahydrofuran / 0.17 h / Heating
4: 60 percent / m-chloroperbenzoic acid / tetrahydrofuran / 1 h / Ambient temperature
With
pyridine; methanol; sodium tetrahydroborate; potassium dihydrogenphosphate; adogen 464; potassium nitrososulfonate; oxygen; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; benzene;
DOI:10.1021/jm00402a009
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 100 percent / HBr / acetic acid / 3.5 h / Heating
2: 80 percent / (KSO3)2NO, aq. KH2PO4, Adogen 464 / CH2Cl2; benzene / 1 h
3: 1.) NaBH4, O2, 2.) pyridine / 1) ethanol, room temperature, 40 h; 2) ether, THF, overnight
4: 86 percent / NaHCO3, CH3OH / tetrahydrofuran / 0.17 h / Heating
5: 60 percent / m-chloroperbenzoic acid / tetrahydrofuran / 1 h / Ambient temperature
With
pyridine; methanol; sodium tetrahydroborate; potassium dihydrogenphosphate; adogen 464; potassium nitrososulfonate; hydrogen bromide; oxygen; sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; dichloromethane; acetic acid; benzene;
DOI:10.1021/jm00402a009