vitamin D₂ 5,6-diol

Base Information

• Chemical Name: vitamin D₂ 5,6-diol
• CAS No.: 125276-73-5
• Molecular Formula: C₂₈H₄₆O₃
• Molecular Weight: 430.671
• Mol file: 125276-73-5.mol

Synonyms:

Chemical Property of vitamin D₂ 5,6-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of vitamin D₂ 5,6-diol

There total 2 articles about vitamin D₂ 5,6-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Calciferol (50-14-6) → vitamin D2 5,6-diol (56282-28-1,125276-73-5)

Guidance literature:

With lead(IV) acetate;

Reference yield:

→ vitamin D2 5,6-diol (56282-28-1,125276-73-5)

Guidance literature:

With potassium hydroxide;

Reference yield:

vitamin D2 5,6-diol (56282-28-1,125276-73-5) → (2Z)-2-<(5S)-5-(tert-butyldimethylsilyloxy)-2-methylene-cyclohexylidene>-ethanol (96685-53-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: imidazole / dimethylformamide

2.1: Pb(OAc)4 / benzene

2.2: Red-Al / toluene

With 1H-imidazole; lead(IV) acetate; In N,N-dimethyl-formamide; benzene; 1.1: silylation / 2.1: oxidative cleavage / 2.2: Reduction;

DOI:10.1016/S0957-4166(00)00239-1

upstream raw materials:

Calciferol

Downstream raw materials:

(2Z)-2-<(5S)-5-(tert-butyldimethylsilyloxy)-2-methylene-cyclohexylidene>-ethanol