5,6-Bis(4-methoxyphenyl)pyrazine-2-carboxylic acid

Base Information

Chemical Name:5,6-Bis(4-methoxyphenyl)pyrazine-2-carboxylic acid
CAS No.:122956-28-9
Molecular Formula:C19H16N2O4
Molecular Weight:336.347
Hs Code.:
DSSTox Substance ID:DTXSID80707202
Nikkaji Number:J899.533H
Wikidata:Q82640886
Mol file:122956-28-9.mol

Synonyms:5,6-Bis(4-methoxyphenyl)pyrazine-2-carboxylic acid;122956-28-9;SCHEMBL4455131;DTXSID80707202

Suppliers and Price of 5,6-Bis(4-methoxyphenyl)pyrazine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 5,6-Bis(4-methoxyphenyl)pyrazine-2-carboxylic acid

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:336.11100700
Heavy Atom Count:25
Complexity:431

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC=C(N=C2C3=CC=C(C=C3)OC)C(=O)O

Technology Process of 5,6-Bis(4-methoxyphenyl)pyrazine-2-carboxylic acid

There total 3 articles about 5,6-Bis(4-methoxyphenyl)pyrazine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 122956-27-8
2,3-bis(p-methoxyphenyl)-5-cyanopyrazine

: 122956-28-9
5,6-bis(4-methoxyphenyl)-pyrazine-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In 1,4-dioxane; methanol; for 4h; Heating;
DOI:10.1248/bpb.20.1076

Reference yield:

: C₁₉H₁₈N₂O₄

: 122956-28-9
5,6-bis(4-methoxyphenyl)-pyrazine-2-carboxylic acid

Guidance literature:: With air; In methanol; for 8h;
DOI:10.1016/j.bmc.2007.03.075

Reference yield:

: 33288-76-5
5,6-bis-(4-methoxyphenyl)-2,3-dihydro-pyrazine

: 122956-28-9
5,6-bis(4-methoxyphenyl)-pyrazine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: diluted alcohol

2: alcoholic KOH-solution

With potassium hydroxide; ethanol;