(2-Chloro-7H-purin-6-yl)-furan-2-ylmethyl-amine

Base Information

• Chemical Name: (2-Chloro-7H-purin-6-yl)-furan-2-ylmethyl-amine
• CAS No.: 101862-47-9
• Molecular Formula: C₁₀H₈ClN₅O
• Molecular Weight: 249.659
• European Community (EC) Number: 890-102-9
• ChEMBL ID: CHEMBL1514018
• Nikkaji Number: J2.853.861H
• NSC Number: 45794
• Mol file: 101862-47-9.mol

Synonyms:(2-Chloro-7H-purin-6-yl)-furan-2-ylmethyl-amine;101862-47-9;2-chloro-N-[(furan-2-yl)methyl]-7H-purin-6-amine;2-Chloro-N6-furfuryladenine;Kinetin derivative 1;2-chloro-N-(furan-2-ylmethyl)-7H-purin-6-amine;SCHEMBL2833837;CHEMBL1514018;SCHEMBL13087414;GLXC-25844;BEA86247;NSC45794;MFCD09792860;NSC-45794;AKOS005559584;AKOS032401256;SB30201;NCGC00168239-01;NCGC00168239-02;BS-52391;HY-125814;CS-0100010;E78403;EN300-307304;(2-Chloro-7H-purin-6-yl)furan-2-ylmethylamine;2-Chloro-N-(2-furanylmethyl)-7H-purin-6-amine

Chemical Property of (2-Chloro-7H-purin-6-yl)-furan-2-ylmethyl-amine

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 249.0417376
• Heavy Atom Count: 17
• Complexity: 269

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-N-[(furan-2-yl)methyl]-7H-purin-6-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=COC(=C1)CNC2=NC(=NC3=C2NC=N3)Cl
• Uses: 2-Chloro-N-[(furan-2-yl)methyl]-7H-purin-6-amine is a chlorinated Kinetin (K570005) which is a cell division factor found in various plant parts and in yeast. 2-Chloro-N-[(furan-2-yl)methyl]-7H-purin-6-amine is used in the synthesis of zinc and copper complexes.

Technology Process of (2-Chloro-7H-purin-6-yl)-furan-2-ylmethyl-amine

There total 2 articles about (2-Chloro-7H-purin-6-yl)-furan-2-ylmethyl-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

furan-2-ylmethanamine (617-89-0) + 2,6 dichloropurine (5451-40-1) → 2-chloro-N-(2-furanylmethyl)-9H-purin-6-amine (101862-47-9,1215269-71-8,1215269-72-9,1215269-73-0,1215269-74-1)

Guidance literature:

With triethylamine; In water; acetonitrile; at 20 - 60 ℃; for 9h;

Reference yield:

→ 2-chloro-N-[(furan-2-yl)methyl]-7H-purin-6-amine (101862-47-9)

Guidance literature:

/BRN= 205920/;

DOI:10.1021/ja01523a075

Reference yield:

2-chloro-N-[(furan-2-yl)methyl]-7H-purin-6-amine (101862-47-9) → furfuryl-(2-hydrazino-7(9)H-purin-6-yl)-amine (7471-66-1)

Guidance literature:

With hydrazine hydrate;

DOI:10.1021/ja01523a075

upstream raw materials:

furan-2-ylmethanamine

2,6 dichloropurine

Downstream raw materials:

furfuryl-(2-hydrazino-7(9)H-purin-6-yl)-amine