Technology Process of C34H35Cl2N3O5
There total 11 articles about C34H35Cl2N3O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 1H-imidazole / N,N-dimethyl-formamide / 20 °C
2: HATU; triethylamine / 20 °C
3: tetrabutyl ammonium fluoride / N,N-dimethyl-formamide / 50 °C
4: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; 1,4-dioxane / 110 °C
5: chloro-trimethyl-silane; sodium iodide / acetonitrile / 20 °C
With
1H-imidazole; tetrakis(triphenylphosphine) palladium(0); chloro-trimethyl-silane; tetrabutyl ammonium fluoride; sodium carbonate; triethylamine; HATU; sodium iodide;
In
1,4-dioxane; water; N,N-dimethyl-formamide; acetonitrile;
4: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.10.095
- Guidance literature:
-
Multi-step reaction with 6 steps
1: lithium hydroxide; sodium hydroxide / methanol; water / 20 °C
2: 1H-imidazole / N,N-dimethyl-formamide / 20 °C
3: HATU; triethylamine / 20 °C
4: tetrabutyl ammonium fluoride / N,N-dimethyl-formamide / 50 °C
5: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; 1,4-dioxane / 110 °C
6: chloro-trimethyl-silane; sodium iodide / acetonitrile / 20 °C
With
1H-imidazole; tetrakis(triphenylphosphine) palladium(0); chloro-trimethyl-silane; tetrabutyl ammonium fluoride; sodium carbonate; triethylamine; HATU; sodium iodide; sodium hydroxide; lithium hydroxide;
In
1,4-dioxane; methanol; water; N,N-dimethyl-formamide; acetonitrile;
5: |Suzuki Coupling;
DOI:10.1016/j.bmcl.2012.10.095