3-(4-Chlorophenyl)-4-phenyl-1,2-oxazol-5(4H)-one

Base Information

Chemical Name:3-(4-Chlorophenyl)-4-phenyl-1,2-oxazol-5(4H)-one
CAS No.:123476-71-1
Molecular Formula:C₁₅H₁₀ClNO₂
Molecular Weight:271.703
Hs Code.:
DSSTox Substance ID:DTXSID30558867
Mol file:123476-71-1.mol

Synonyms:123476-71-1;3-(4-Chlorophenyl)-4-phenylisoxazol-5(4H)-one;3-(4-Chlorophenyl)-4-phenyl-1,2-oxazol-5(4H)-one;DTXSID30558867

Suppliers and Price of 3-(4-Chlorophenyl)-4-phenyl-1,2-oxazol-5(4H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-(4-Chlorophenyl)-4-phenyl-1,2-oxazol-5(4H)-one

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:271.0400063
Heavy Atom Count:19
Complexity:368

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2C(=NOC2=O)C3=CC=C(C=C3)Cl

Technology Process of 3-(4-Chlorophenyl)-4-phenyl-1,2-oxazol-5(4H)-one

There total 1 articles about 3-(4-Chlorophenyl)-4-phenyl-1,2-oxazol-5(4H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 101-41-7
benzeneacetic acid methyl ester

: 28123-63-9
4-chlorobenzohydroximoyl chloride

: 123476-71-1
3-(4-chlorophenyl)-4-phenylisoxazol-5(4H)-one

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) THF, n-hexan, -78 deg C, 10 min, 2.) -78 deg C --> r.t., 12 h;
DOI:10.1055/s-1989-27221

Reference yield:

: 123476-71-1
3-(4-chlorophenyl)-4-phenylisoxazol-5(4H)-one

: 123477-01-0
N-[3-(4-Chloro-phenyl)-4-phenyl-isoxazol-5-yl]-N'-methyl-ethane-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) POCl₃, 2.) Et₃N / 2.) 100-110 deg C, 1.5 h

2: 28 percent / tetrahydrofuran / 24 h / Heating

With triethylamine; trichlorophosphate; In tetrahydrofuran;
DOI:10.1055/s-1989-27221

Reference yield:

: 123476-71-1
3-(4-chlorophenyl)-4-phenylisoxazol-5(4H)-one

: 123477-04-3
N¹-[3-(4-Chloro-phenyl)-4-phenyl-isoxazol-5-yl]-butane-1,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) POCl₃, 2.) Et₃N / 2.) 100-110 deg C, 1.5 h

2: 70 percent / tetrahydrofuran / 24 h / Heating

With triethylamine; trichlorophosphate; In tetrahydrofuran;
DOI:10.1055/s-1989-27221