2α-Bromo-3-cholestanone

Base Information

• Chemical Name: 2α-Bromo-3-cholestanone
• CAS No.: 23737-88-4
• Molecular Formula: C₂₇H₄₅BrO
• Molecular Weight: 465.558
• Mol file: 23737-88-4.mol

Synonyms:

Chemical Property of 2α-Bromo-3-cholestanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2α-Bromo-3-cholestanone

There total 15 articles about 2α-Bromo-3-cholestanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

3-Acetoxy-5α-Δ2-Cholesten (1255-89-6,16374-67-7,22799-07-1) → 2α-Brom-cholestanon-(3) (1452-34-2,2042-08-2,22164-15-4,23737-88-4,41602-10-2,51014-33-6,57794-47-5)

Guidance literature:

With lead(IV) acetate; zinc dibromide; In diethyl ether; at 0 ℃; for 0.166667h;

DOI:10.1055/s-1982-30047

Reference yield:

→ 2α-Brom-cholestan-3-on (1452-34-2,2042-08-2,22164-15-4,23737-88-4,41602-10-2,51014-33-6,57794-47-5)

Guidance literature:

2β-Brom-cholestanon-(3), HBr in Eg., 20grad, quant. Ausb.;

DOI:10.1021/ja01505a044

Reference yield:

→ 2β-Brom-5α-cholestan-3-on (1452-34-2,2042-08-2,22164-15-4,23737-88-4,41602-10-2,51014-33-6,57794-47-5)

Guidance literature:

in geringer Menge aus 3-Acetoxy-cholesten-(2), Br2 in Eg.-Tetrachlorkohlenstoff (neben 2α-Brom-cholestanon-(3));

DOI:10.1021/ja01505a044

upstream raw materials:

3-Acetoxy-5α-Δ²-Cholesten

Downstream raw materials:

Cholestano-2'-phenyl<2,3-d>triazole

Cholestanone-2,3-dione bisphenylhydrazone