(4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ⁴-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester

Base Information

• Chemical Name: (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ⁴-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester
• CAS No.: 66095-01-0
• Molecular Formula: C₃₁H₂₇N₅O₉S
• Molecular Weight: 645.649

Synonyms:

Chemical Property of (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ⁴-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ⁴-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester

There total 2 articles about (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ⁴-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(5R)-3-methyl-4-methylene-5t,8-dioxo-7t-(2-phenoxy-acetylamino)-(6rH)-5λ4-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester (66138-37-2) → (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ4-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester (66095-01-0)

Guidance literature:

Multi-step reaction with 2 steps

1: Ph₂SNH / dimethylformamide / 0 °C

With Ph₂SnH; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(01)83306-2

Reference yield:

phenyl isocyanate (103-71-9) + (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-(4'rN,6'cH)-5'λ4-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester (66094-92-6) → (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ4-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester (66095-01-0)

Guidance literature:

DOI:10.1016/S0040-4039(01)83306-2

upstream raw materials:

phenyl isocyanate

(4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-(4'rN,6'cH)-5'λ⁴-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester

(5R)-3-methyl-4-methylene-5t,8-dioxo-7t-(2-phenoxy-acetylamino)-(6rH)-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 66095-01-0 (4'R)-3'-methyl-5't,8'-dioxo-7't-(2-phenoxy-acetylamino)-1-phenylcarbamoyl-(4'rN,6'cH)-5'λ⁴-spiro[aziridine-2,4'-(5-thia-1-aza-bicyclo[4.2.0]oct-2-ene)]-2'-carboxylic acid 4-nitro-benzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send