(10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene

Base Information

• Chemical Name: (10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene
• CAS No.: 138706-00-0
• Molecular Formula: C₃₆H₅₅NO₄
• Molecular Weight: 565.837
• Mol file: 138706-00-0.mol

Synonyms:

Chemical Property of (10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene

There total 4 articles about (10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

24αF-ethyl-5α-cholesten-(14)-ol-(3β) (81241-57-8) → (10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene (138706-00-0)

Guidance literature:

Multi-step reaction with 3 steps

2: platinum; glacial acetic acid / Hydrogenation_.Hydrlylse des gebildeten O-Acetyl-Derivats

With acetic acid; platinum;

DOI:10.1021/ja01327a039

Reference yield:

3β-acetoxy-5α-stigmastene-(14) (63631-47-0) → (10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene (138706-00-0)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; glacial acetic acid / Hydrogenation_.Hydrlylse des gebildeten O-Acetyl-Derivats

With acetic acid; platinum;

DOI:10.1021/ja01327a039

Reference yield:

(24R)-α-ethyl-5α-cholest-8(14)-en-3β-ol acetate (14291-39-5) → (10S)-3c-(4-nitro-benzoyloxy)-10-r.13c-dimethyl-17c-((1R:4R)-1.5-dimethyl-4-ethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene (138706-00-0)

Guidance literature:

Multi-step reaction with 4 steps

1: HCl; chloroform / 0 °C / Behandeln des erhaltenen Isomerisierungsprodukts mit aethanol. KOH; Reinigung ueber das O-<4-Nitro-benzoyl>-Derivat

3: platinum; glacial acetic acid / Hydrogenation_.Hydrlylse des gebildeten O-Acetyl-Derivats

With hydrogenchloride; chloroform; acetic acid; platinum;

DOI:10.1021/ja01327a039

upstream raw materials:

Stigmastanol

24α_F-ethyl-5α-cholesten-(14)-ol-(3β)

3β-acetoxy-5α-stigmastene-(14)

(24R)-α-ethyl-5α-cholest-8(14)-en-3β-ol acetate