8-Methoxy-2,4-bis(2-methylphenylamino)quinazoline

Base Information

Chemical Name:8-Methoxy-2,4-bis(2-methylphenylamino)quinazoline
CAS No.:124309-34-8
Molecular Formula:C23H22N4O
Molecular Weight:370.454
Hs Code.:
DSSTox Substance ID:DTXSID60437333
Wikidata:Q82252818
ChEMBL ID:CHEMBL319377
Mol file:124309-34-8.mol

Synonyms:TCMDC-142321;CHEMBL319377;124309-34-8;8-Methoxy-2,4-bis(2-methylphenylamino)quinazoline;SCHEMBL9508885;DTXSID60437333;NRNFZLGTTZCKCI-UHFFFAOYSA-N;BDBM50032114;8-Methoxy-N*2*,N*4*-di-o-tolyl-quinazoline-2,4-diamine;8-methoxy-2-N,4-N-bis(2-methylphenyl)quinazoline-2,4-diamine

Suppliers and Price of 8-Methoxy-2,4-bis(2-methylphenylamino)quinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 8-Methoxy-2,4-bis(2-methylphenylamino)quinazoline

Chemical Property:

XLogP3:6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:370.17936134
Heavy Atom Count:28
Complexity:489

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC2=NC(=NC3=C2C=CC=C3OC)NC4=CC=CC=C4C

Technology Process of 8-Methoxy-2,4-bis(2-methylphenylamino)quinazoline

There total 5 articles about 8-Methoxy-2,4-bis(2-methylphenylamino)quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 124309-69-9
2-chloro-8-methoxy-4-<(2-methylphenyl)amino>quinazoline

: 95-53-4
o-toluidine

: 124309-34-8
8-methoxy-2,4-bis(2-methylphenylamino)quinazoline

Guidance literature:: In ethanol;

Reference yield:

: 4920-80-3
3-methoxy-2-nitrobenzoic acid

: 124309-34-8
8-methoxy-2,4-bis(2-methylphenylamino)quinazoline

Guidance literature:: Multi-step reaction with 5 steps

1: palladium/charcoal / ethanol

2: sodium hydroxide / water; acetic acid

3: N,N-dimethyl-aniline; trichlorophosphate

4: sodium hydroxide; sodium acetate / tetrahydrofuran; water

5: ethanol

With sodium hydroxide; sodium acetate; palladium/charcoal; In tetrahydrofuran; ethanol; water; acetic acid; N,N-dimethyl-aniline; trichlorophosphate;

Reference yield:

: 3177-80-8
2-amino-3-methoxybenzoic acid

: 124309-34-8
8-methoxy-2,4-bis(2-methylphenylamino)quinazoline

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / water; acetic acid

2: N,N-dimethyl-aniline; trichlorophosphate

3: sodium hydroxide; sodium acetate / tetrahydrofuran; water

4: ethanol

With sodium hydroxide; sodium acetate; In tetrahydrofuran; ethanol; water; acetic acid; N,N-dimethyl-aniline; trichlorophosphate;