N-(1-Phenyl-ethyl)-isonicotinamide

Base Information

Chemical Name:N-(1-Phenyl-ethyl)-isonicotinamide
CAS No.:2909-34-4
Molecular Formula:C₁₄H₁₄N₂O
Molecular Weight:226.278
Hs Code.:
DSSTox Substance ID:DTXSID601329594
ChEMBL ID:CHEMBL1408974

Synonyms:N-(1-Phenyl-ethyl)-isonicotinamide;N-(1-phenylethyl)pyridine-4-carboxamide;TimTec1_002956;Oprea1_275524;Oprea1_451150;MLS001209318;SCHEMBL1568720;CHEMBL1408974;DTXSID601329594;HMS1542G08;HMS2833B03;STK015465;AKOS000629674;AKOS016194226;N-(1-Phenylethyl)-4-pyridinecarboxamide;SMR000514589;SR-01000319832;SR-01000319832-1;BRD-A66321421-001-01-7;2909-34-4

Suppliers and Price of N-(1-Phenyl-ethyl)-isonicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(1-Phenyl-ethyl)-isonicotinamide

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:226.110613074
Heavy Atom Count:17
Complexity:243

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NC(=O)C2=CC=NC=C2

Technology Process of N-(1-Phenyl-ethyl)-isonicotinamide

There total 5 articles about N-(1-Phenyl-ethyl)-isonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 100-48-1
pyridine-4-carbonitrile

: 98-85-1,13323-81-4
1-Phenylethanol

: 2909-34-4,35354-24-6
N-(1-phenylethyl)isonicotinamide

Guidance literature:: With sulfated tungstate; at 100 ℃; for 4.5h; Neat (no solvent);
DOI:10.1039/c0gc00759e

Reference yield:

: 6320-63-4
isonicotinic acid benzylamide

: 2909-34-4,35354-24-6
N-(1-phenylethyl)isonicotinamide

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) THF, hexane, -78 deg C, 1 h, then to r.t., 1 h, 2.) -78 deg C, 30 min; 25 deg C, 1.5 h;

Reference yield:

: 39178-35-3
isonicotinoyl chloride hydrochloride

: 2909-34-4,35354-24-6
N-(1-phenylethyl)isonicotinamide

Guidance literature:: Multi-step reaction with 2 steps

2: 1.) n-BuLi / 1.) THF, hexane, -78 deg C, 1 h, then to r.t., 1 h, 2.) -78 deg C, 30 min; 25 deg C, 1.5 h

With n-butyllithium;