1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate

Base Information

• Chemical Name: 1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate
• CAS No.: 116438-47-2
• Molecular Formula: 2C₇H₈O₃S*C₂₀H₂₁N₃O₂
• Molecular Weight: 679.815
• Mol file: 116438-47-2.mol

Synonyms:

Chemical Property of 1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate

There total 3 articles about 1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-benzyl-L-histidine (16832-24-9,103772-40-3,31534-22-2) + toluene-4-sulfonic acid (104-15-4) + benzyl alcohol (100-51-6,185532-71-2) → 1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate (116438-47-2)

Guidance literature:

In tetrachloromethane; Heating;

DOI:10.1021/jm00126a030

Reference yield:

benzyl chloride (100-44-7) → 1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate (116438-47-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 56 percent / liquid ammonia, Na / -70 °C

2: 83 percent / CCl₄ / Heating

With ammonia; sodium; In tetrachloromethane;

DOI:10.1021/jm00126a030

Reference yield:

L-histidine (71-00-1,26062-48-6,90081-11-1) → 1-benzyl-L-histidine benzyl ester di-p-toluene sulfonate (116438-47-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 56 percent / liquid ammonia, Na / -70 °C

2: 83 percent / CCl₄ / Heating

With ammonia; sodium; In tetrachloromethane;

DOI:10.1021/jm00126a030

upstream raw materials:

1-benzyl-L-histidine

toluene-4-sulfonic acid

benzyl alcohol

benzyl chloride