Technology Process of Boc-Thr(Bzl)-Cys(Bzl)-Met-Thr(Bzl)-Thr(Bzl)-Ala-Gln-Gly-OH
There total 15 articles about Boc-Thr(Bzl)-Cys(Bzl)-Met-Thr(Bzl)-Thr(Bzl)-Ala-Gln-Gly-OH which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 13 steps
1: 57.8 percent / triethylamine / dimethylformamide
2: H2 / Pd/C / dimethylformamide
3: dimethylformamide
4: 74 percent / H2 / Pd/C / dimethylformamide
5: 75.6 percent / triethylamine / dimethylformamide
6: 96 percent / 4 M HCl in acetic acid / 1 h
7: 95.8 percent / dimethylformamide
8: 4 M HCl in acetic acid / 0.25 h
9: triethylamine / dimethylformamide / 5 h / pH 7.5
10: 4 M HCl / dioxane / 0.5 h
11: triethylamine / dimethylformamide / 2 h / pH 7.5
12: 4 M HCl / dioxane / 0.5 h
13: triethylamine / dimethylformamide / 55.5 h / 40 °C
With
hydrogenchloride; hydrogen; triethylamine;
palladium on activated charcoal;
In
1,4-dioxane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 11 steps
1: dimethylformamide
2: 74 percent / H2 / Pd/C / dimethylformamide
3: 75.6 percent / triethylamine / dimethylformamide
4: 96 percent / 4 M HCl in acetic acid / 1 h
5: 95.8 percent / dimethylformamide
6: 4 M HCl in acetic acid / 0.25 h
7: triethylamine / dimethylformamide / 5 h / pH 7.5
8: 4 M HCl / dioxane / 0.5 h
9: triethylamine / dimethylformamide / 2 h / pH 7.5
10: 4 M HCl / dioxane / 0.5 h
11: triethylamine / dimethylformamide / 55.5 h / 40 °C
With
hydrogenchloride; hydrogen; triethylamine;
palladium on activated charcoal;
In
1,4-dioxane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 12 steps
1: H2 / Pd/C / dimethylformamide
2: dimethylformamide
3: 74 percent / H2 / Pd/C / dimethylformamide
4: 75.6 percent / triethylamine / dimethylformamide
5: 96 percent / 4 M HCl in acetic acid / 1 h
6: 95.8 percent / dimethylformamide
7: 4 M HCl in acetic acid / 0.25 h
8: triethylamine / dimethylformamide / 5 h / pH 7.5
9: 4 M HCl / dioxane / 0.5 h
10: triethylamine / dimethylformamide / 2 h / pH 7.5
11: 4 M HCl / dioxane / 0.5 h
12: triethylamine / dimethylformamide / 55.5 h / 40 °C
With
hydrogenchloride; hydrogen; triethylamine;
palladium on activated charcoal;
In
1,4-dioxane; N,N-dimethyl-formamide;
