Isoquinoline, 3,4-dihydro-6-methoxy-1-[[3,5-dibenzyloxyphenyl]methyl]-

Base Information

Chemical Name:Isoquinoline, 3,4-dihydro-6-methoxy-1-[[3,5-dibenzyloxyphenyl]methyl]-
CAS No.:79087-59-5
Molecular Formula:C₃₁H₂₉NO₃
Molecular Weight:463.576
Hs Code.:
DSSTox Substance ID:DTXSID801145009

Synonyms:DTXSID801145009;1-[3,5-Bis(benzyloxy)benzyl]-6-methoxy-3,4-dihydroisoquinoline #;1-[[3,5-Bis(phenylmethoxy)phenyl]methyl]-3,4-dihydro-6-methoxyisoquinoline;Isoquinoline, 3,4-dihydro-6-methoxy-1-[[3,5-dibenzyloxyphenyl]methyl]-;79087-59-5

Suppliers and Price of Isoquinoline, 3,4-dihydro-6-methoxy-1-[[3,5-dibenzyloxyphenyl]methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Isoquinoline, 3,4-dihydro-6-methoxy-1-[[3,5-dibenzyloxyphenyl]methyl]-

Chemical Property:

XLogP3:6.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:463.21474379
Heavy Atom Count:35
Complexity:624

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=NCC2)CC3=CC(=CC(=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5

Technology Process of Isoquinoline, 3,4-dihydro-6-methoxy-1-[[3,5-dibenzyloxyphenyl]methyl]-

There total 6 articles about Isoquinoline, 3,4-dihydro-6-methoxy-1-[[3,5-dibenzyloxyphenyl]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

: 76787-08-1
1-(3',5'-dibenzyloxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline

: 79087-59-5
1-<3',5-bis(benzyloxy)benzyl>-6-methoxy-3,4-dihydroisoquinoline

Guidance literature:: palladium on activated charcoal; In toluene; for 100.5h; Heating;
DOI:10.1002/hlca.19810640310

Reference yield:

: 80907-81-9
N-(3-methoxyphenethyl)-2-<3,5-bis(benzyloxy)phenyl>acetamide

: 79087-59-5
1-<3',5-bis(benzyloxy)benzyl>-6-methoxy-3,4-dihydroisoquinoline

Guidance literature:: Bischler - Napieralski reaction;
DOI:10.1002/hlca.19800630731

Reference yield:

: 2732-96-9
3,5-dibenzyloxyphenylacetic acid

: 79087-59-5
1-<3',5-bis(benzyloxy)benzyl>-6-methoxy-3,4-dihydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / 2 h / 185 °C

2: POCl₃ / acetonitrile / 1.5 h / Heating

With trichlorophosphate; In acetonitrile;
DOI:10.1002/hlca.19820650531