5-hydroxyformylkynurenine

Base Information

• Chemical Name: 5-hydroxyformylkynurenine
• CAS No.: 84589-02-6
• Molecular Formula: C₁₁H₁₂N₂O₅
• Molecular Weight: 252.227
• Mol file: 84589-02-6.mol

Synonyms:

Chemical Property of 5-hydroxyformylkynurenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-hydroxyformylkynurenine

There total 7 articles about 5-hydroxyformylkynurenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

3a-hydroxy-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole-2-carboxylic acid (35169-97-2) → 5-hydroxyformylkynurenine (84589-02-6)

Guidance literature:

With oxygen; Irradiation; phosphat buffer;

DOI:10.1016/S0040-4020(01)96583-4

Reference yield:

3a-hydroperoxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid (70938-99-7) → 2-amino-4-(2-formamidophenyl)-4-oxo-butanoic acid (1022-31-7,3978-11-8) + 5-hydroxyformylkynurenine (84589-02-6) + 3a-hydroxy-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole-2-carboxylic acid (35169-97-2)

Guidance literature:

With dimethylsulfide; oxygen; Yield given. Multistep reaction. Yields of byproduct given; 1.) methylene blue, EtOH, 1.5 h, phosphate buffer, 2.) 5percent HCl;

DOI:10.1016/S0040-4020(01)96583-4

Reference yield:

3a-hydroperoxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid (70938-99-7) → 5-hydroxyformylkynurenine (84589-02-6)

Guidance literature:

With sodium tetrahydroborate; oxygen; Yield given. Multistep reaction; 1.) methylene blue, EtOH, 1.5 h, phosphat buffer, heating, irradiation, RT;

DOI:10.1016/S0040-4020(01)96583-4

upstream raw materials:

3a-hydroperoxy-1,2,3,3a,8,8a-hexahydro-pyrrolo[2,3-b]indole-2-carboxylic acid

3a,5-dihydroxypyrroloindole

3a-hydroxy-1,2,3,3a,8,8a-hexahydropyrrolo<2,3-b>indole-2-carboxylic acid

L-Tryptophan

Downstream raw materials:

5-hydroxykynurenine