Technology Process of 3β-hydroxy-4aα-methyl-A-homo-B,19-dinor-5β,10α-androstan-17-one 3-cyclohexanecarboxylate
There total 8 articles about 3β-hydroxy-4aα-methyl-A-homo-B,19-dinor-5β,10α-androstan-17-one 3-cyclohexanecarboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: aq. sodium hydrogen phosphate, aq. peroxyacetic acid / CHCl3 / 2 h
2: 87 percent / 72percent aq. perchloric acid / dioxane; acetone / 3 h
3: 2.) H2SO4 / 1.) reflux, 2.) a) 30 deg C, 30 min, b) 20 deg C, 2 h
4: 82 percent / conc. HCl / methanol; CHCl3 / 60 h / 35 °C
5: 90 percent / pyridine / 1 h / 0 °C
6: 46 percent / silver acetate, pyridine / 22 h / Heating
7: H2 / Adams cat. / acetic acid / 8 h
8: Jones reagent / acetone / 0.17 h / 20 °C
With
pyridine; hydrogenchloride; peracetic acid; disodium hydrogenphosphate; perchloric acid; jones reagent; sulfuric acid; hydrogen; silver(I) acetate;
platinum(IV) oxide;
In
1,4-dioxane; methanol; chloroform; acetic acid; acetone;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 2.) H2SO4 / 1.) reflux, 2.) a) 30 deg C, 30 min, b) 20 deg C, 2 h
2: 82 percent / conc. HCl / methanol; CHCl3 / 60 h / 35 °C
3: 90 percent / pyridine / 1 h / 0 °C
4: 46 percent / silver acetate, pyridine / 22 h / Heating
5: H2 / Adams cat. / acetic acid / 8 h
6: Jones reagent / acetone / 0.17 h / 20 °C
With
pyridine; hydrogenchloride; jones reagent; sulfuric acid; hydrogen; silver(I) acetate;
platinum(IV) oxide;
In
methanol; chloroform; acetic acid; acetone;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 87 percent / 72percent aq. perchloric acid / dioxane; acetone / 3 h
2: 2.) H2SO4 / 1.) reflux, 2.) a) 30 deg C, 30 min, b) 20 deg C, 2 h
3: 82 percent / conc. HCl / methanol; CHCl3 / 60 h / 35 °C
4: 90 percent / pyridine / 1 h / 0 °C
5: 46 percent / silver acetate, pyridine / 22 h / Heating
6: H2 / Adams cat. / acetic acid / 8 h
7: Jones reagent / acetone / 0.17 h / 20 °C
With
pyridine; hydrogenchloride; perchloric acid; jones reagent; sulfuric acid; hydrogen; silver(I) acetate;
platinum(IV) oxide;
In
1,4-dioxane; methanol; chloroform; acetic acid; acetone;
