3-hydroxybenzaldehyde thiosemicarbazone

Base Information

• Chemical Name: 3-hydroxybenzaldehyde thiosemicarbazone
• CAS No.: 1334180-04-9
• Molecular Formula: C₈H₉N₃OS
• Molecular Weight: 195.245
• Mol file: 1334180-04-9.mol

Synonyms:

Chemical Property of 3-hydroxybenzaldehyde thiosemicarbazone

Chemical Property:

• Boiling Point: 396.7±44.0 °C(Predicted)
• PKA: 8.91±0.10(Predicted)
• Density: 1.34±0.1 g/cm3(Predicted)

Purity/Quality:

3-hydroxybenzaldehydethiosemicarbazone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-hydroxybenzaldehyde thiosemicarbazone

There total 4 articles about 3-hydroxybenzaldehyde thiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

thiosemicarbazide (79-19-6) + meta-hydroxybenzaldehyde (100-83-4) → (3-hydroxybenzylidenehydrazinyl)thiocarboxamide (7420-37-3,1334180-04-9)

Guidance literature:

In ethanol; at 65 ℃; for 6h;

Reference yield: 88.0%

→ (3-hydroxybenzylidenehydrazinyl)thiocarboxamide (7420-37-3,1334180-04-9)

Guidance literature:

Reference yield:

thiosemicarbazide (79-19-6) + meta-hydroxybenzaldehyde (100-83-4) → M-hydroxybenzaldehyde thiosemicarbazone (1334180-04-9)

Guidance literature:

With acetic acid; In ethanol; Reflux;

DOI:10.1016/j.ejmech.2013.08.054

upstream raw materials:

thiosemicarbazide

meta-hydroxybenzaldehyde

thiosemicarbazide hydrochloride

Downstream raw materials:

Cu⁽¹⁺⁾*C₈H₈N₃OS^(1-)={Cu(C₆H₄(OH)CHNNCSNH₂)}

ethyl 2-[(E)-2-[(3-hydroxyphenyl)methylidene]hydrazin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate