(S) 4'-trifluoromethylbiphenyl-2-carboxylic acid (4-{[(benzylcarbamoyl-phenyl-methyl)carbamoyl]methylsulfanyl}phenyl)amide

Base Information

• Chemical Name: (S) 4'-trifluoromethylbiphenyl-2-carboxylic acid (4-{[(benzylcarbamoyl-phenyl-methyl)carbamoyl]methylsulfanyl}phenyl)amide
• CAS No.: 720682-99-5
• Molecular Formula: C₃₇H₃₀F₃N₃O₃S
• Molecular Weight: 653.725
• Mol file: 720682-99-5.mol

Synonyms:

Chemical Property of (S) 4'-trifluoromethylbiphenyl-2-carboxylic acid (4-{[(benzylcarbamoyl-phenyl-methyl)carbamoyl]methylsulfanyl}phenyl)amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S) 4'-trifluoromethylbiphenyl-2-carboxylic acid (4-{[(benzylcarbamoyl-phenyl-methyl)carbamoyl]methylsulfanyl}phenyl)amide

There total 2 articles about (S) 4'-trifluoromethylbiphenyl-2-carboxylic acid (4-{[(benzylcarbamoyl-phenyl-methyl)carbamoyl]methylsulfanyl}phenyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-phenylsulfanyl}-acetic acid (889864-55-5) + (S)-2-amino-N-benzyl-2-phenylacetamide (155322-81-9) → (S) 4'-trifluoromethylbiphenyl-2-carboxylic acid (4-{[(benzylcarbamoyl-phenyl-methyl)carbamoyl]methylsulfanyl}phenyl)amide (720682-99-5)

Guidance literature:

With benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/j.bmcl.2006.02.058

Reference yield:

→ (S) 4'-trifluoromethylbiphenyl-2-carboxylic acid (4-{[(benzylcarbamoyl-phenyl-methyl)carbamoyl]methylsulfanyl}phenyl)amide (720682-99-5)

Guidance literature:

upstream raw materials:

{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-phenylsulfanyl}-acetic acid

(S)-2-amino-N-benzyl-2-phenylacetamide