2-Piperidinecarboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-

Base Information

Chemical Name:2-Piperidinecarboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-
CAS No.:124981-17-5
Molecular Formula:C13H17NO3S
Molecular Weight:267.349
Hs Code.:
DSSTox Substance ID:DTXSID90456714
Nikkaji Number:J1.648.771F
Mol file:124981-17-5.mol

Synonyms:2-Piperidinecarboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-;124981-17-5;1-Tosylpiperidine-2-carbaldehyde;DTXSID90456714;AKOS013159631

Suppliers and Price of 2-Piperidinecarboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Piperidinecarboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:267.09291458
Heavy Atom Count:18
Complexity:380

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CCCCC2C=O

Technology Process of 2-Piperidinecarboxaldehyde, 1-[(4-methylphenyl)sulfonyl]-

There total 7 articles about 2-Piperidinecarboxaldehyde, 1-[(4-methylphenyl)sulfonyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 60343-64-8
[1-(toluene-4-sulfonyl)piperidin-2-yl]methanol

: 124981-17-5
1-(4-methylbenzenesulfonyl)piperidine-2-carboxaldehyde

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1002/anie.200804188

Reference yield:

: 144630-21-7
2-<1-(4-methylbenzenesulfonyl)piperidin-2-yl>-1,3-dithiane

: 124981-17-5
1-(4-methylbenzenesulfonyl)piperidine-2-carboxaldehyde

Guidance literature:: With bis-[(trifluoroacetoxy)iodo]benzene; In dichloromethane; for 0.0833333h; Ambient temperature;
DOI:10.1016/S0040-4020(01)90368-0

Reference yield:

: 144630-12-6
2-(piperidin-2-yl)-1,3-dithiane

: 124981-17-5
1-(4-methylbenzenesulfonyl)piperidine-2-carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / pyridine, DMAP / CH₂Cl₂ / 12 h / 0 °C

2: 74 percent Spectr_. / bis(trifluoroacetoxy)iodobenzene / CH₂Cl₂ / 0.08 h / Ambient temperature

With pyridine; dmap; bis-[(trifluoroacetoxy)iodo]benzene; In dichloromethane;
DOI:10.1016/S0040-4020(01)90368-0