2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.0^5,9.0^6,10>dodec-11-en-7-one ethylene acetal

Base Information

• Chemical Name: 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.0^5,9.0^6,10>dodec-11-en-7-one ethylene acetal
• CAS No.: 108418-64-0
• Molecular Formula: C₁₉H₂₁N₃O₃
• Molecular Weight: 339.394

Synonyms:

Chemical Property of 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.0^5,9.0^6,10>dodec-11-en-7-one ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.0^5,9.0^6,10>dodec-11-en-7-one ethylene acetal

There total 13 articles about 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.0^5,9.0^6,10>dodec-11-en-7-one ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

4-phenyl-2,4,6-triazapentacyclo<6.5.2.02,6.08,12.09,13>pentadec-14-ene-3,5,10-trione 10-ethylene acetal (108418-63-9,108507-69-3) → 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.05,9.06,10>dodec-11-en-7-one ethylene acetal (108418-64-0,108507-70-6)

Guidance literature:

With potassium hydroxide; In water; dimethyl sulfoxide; at 50 ℃; for 3h;

DOI:10.1021/jo00389a003

Reference yield:

4-Phenyl-1,2,4-triazolidine-3,5-dione (4233-33-4) → 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.05,9.06,10>dodec-11-en-7-one ethylene acetal (108418-64-0,108507-70-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / CH₂Cl₂ / 3 h / Ambient temperature

2: 80 percent / KOH / H₂O; dimethylsulfoxide / 3 h / 50 °C

With potassium hydroxide; In dichloromethane; water; dimethyl sulfoxide;

DOI:10.1021/jo00389a003

Reference yield:

cyclodeca-3,8-diene-1,6-dione bis(ethylene acetal) (22464-22-8) → 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.05,9.06,10>dodec-11-en-7-one ethylene acetal (108418-64-0,108507-70-6)

Guidance literature:

Multi-step reaction with 12 steps

1: 61 percent / 80percent m-chloroperoxybenzoic acid, sodium hydrogencarbonate / CH₂Cl₂ / 40 h / Ambient temperature

2: 1.) diphenyl diselenide, NaBH₄, 2.) 30percent H₂O₂ / 1.) n-BuOH, reflux , 20 h, 2.) n-BuOH, THF, 16 h

3: 50 percent / chromium trioxide / pyridine; CH₂Cl₂ / 36 h / Ambient temperature

4: 85 percent / acetonitrile / 14 h / 0 °C / Irradiation

5: 95 percent / sodium borohydride / ethanol / 12 h

6: 79 percent / pyridine / 120 h / 5 °C

7: 65 percent / 1.5-diazabicyclo<4.3.0>non-5-ene / acetonitrile / 15 h / 80 °C

8: 90 percent / p-toluenesulfonic acid monohydrate / H₂O; acetone / 0.33 h / Ambient temperature

9: 91 percent / lithium aluminium hydride / diethyl ether / 3 h / Heating

10: 85 percent / methyltriphenoxyphosphonium iodide / hexamethylphosphoric acid triamide / 5 h / 95 °C

11: 85 percent / CH₂Cl₂ / 3 h / Ambient temperature

12: 80 percent / KOH / H₂O; dimethylsulfoxide / 3 h / 50 °C

With chromium(VI) oxide; potassium hydroxide; sodium tetrahydroborate; lithium aluminium tetrahydride; diphenyl diselenide; DBN; methyltriphenoxyphosphonium iodide; dihydrogen peroxide; sodium hydrogencarbonate; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In pyridine; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; ethanol; dichloromethane; water; dimethyl sulfoxide; acetone; acetonitrile;

DOI:10.1021/jo00389a003

upstream raw materials:

4-phenyl-2,4,6-triazapentacyclo<6.5.2.0^2,6.0^8,12.0^9,13>pentadec-14-ene-3,5,10-trione 10-ethylene acetal

4-Phenyl-1,2,4-triazolidine-3,5-dione

cyclodeca-3,8-diene-1,6-dione bis(ethylene acetal)

tricyclo<5.3.0.0^2,8>dec-5-ene-4,9-dione 9-ethylene acetal

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 108418-64-0 2-(N-phenylcarbamoyl)-2,3-diazatetracyclo<6.2.2.0^5,9.0^6,10>dodec-11-en-7-one ethylene acetal

Send

Send

Metric Ton KG G Pound L ML

Send

Send