Pyrido[2,3-d]pyridazine-8-carboxylic acid, 2,4-diamino-6-(4-chlorophenyl)-3-cyano-5,6-dihydro-5-imino-, ethyl ester

Base Information

Chemical Name:Pyrido[2,3-d]pyridazine-8-carboxylic acid, 2,4-diamino-6-(4-chlorophenyl)-3-cyano-5,6-dihydro-5-imino-, ethyl ester
CAS No.:125041-02-3
Molecular Formula:C₁₇H₁₄ClN₇O₂
Molecular Weight:383.797
Hs Code.:
Mol file:125041-02-3.mol

Synonyms:

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Chemical Property of Pyrido[2,3-d]pyridazine-8-carboxylic acid, 2,4-diamino-6-(4-chlorophenyl)-3-cyano-5,6-dihydro-5-imino-, ethyl ester

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Technology Process of Pyrido[2,3-d]pyridazine-8-carboxylic acid, 2,4-diamino-6-(4-chlorophenyl)-3-cyano-5,6-dihydro-5-imino-, ethyl ester

There total 3 articles about Pyrido[2,3-d]pyridazine-8-carboxylic acid, 2,4-diamino-6-(4-chlorophenyl)-3-cyano-5,6-dihydro-5-imino-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 125040-99-5
[(4-Chloro-phenyl)-hydrazono]-(4,6-diamino-3,5-dicyano-pyridin-2-yl)-acetic acid ethyl ester

: 125041-02-3
2,4-Diamino-6-(4-chloro-phenyl)-3-cyano-5-imino-5,6-dihydro-pyrido[2,3-d]pyridazine-8-carboxylic acid ethyl ester

Guidance literature:: In acetic acid; for 2h; Heating;

Reference yield:

: 868-54-2
1,1,3-tricyano-2-amino-1-propene

: 125041-02-3
2,4-Diamino-6-(4-chloro-phenyl)-3-cyano-5-imino-5,6-dihydro-pyrido[2,3-d]pyridazine-8-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: TEA / CHCl₃ / 2 h / Heating

2: 80 percent / sodium acetate / dimethylformamide; ethanol / 2 h / Ambient temperature

3: 60 percent / acetic acid / 2 h / Heating

With TEA; sodium acetate; In ethanol; chloroform; acetic acid; N,N-dimethyl-formamide;

Reference yield:

: 104720-41-4
Ethyl α-(2,4-diamino-3,5-dicyano-6-pyridinyl)-acetate

: 125041-02-3
2,4-Diamino-6-(4-chloro-phenyl)-3-cyano-5-imino-5,6-dihydro-pyrido[2,3-d]pyridazine-8-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / sodium acetate / dimethylformamide; ethanol / 2 h / Ambient temperature

2: 60 percent / acetic acid / 2 h / Heating

With sodium acetate; In ethanol; acetic acid; N,N-dimethyl-formamide;