1-cyanochrysene

Base Information

• Chemical Name: 1-cyanochrysene
• CAS No.: 68723-52-4
• Molecular Formula: C₁₉H₁₁N
• Molecular Weight: 253.303
• Mol file: 68723-52-4.mol

Synonyms:

Chemical Property of 1-cyanochrysene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-cyanochrysene

There total 3 articles about 1-cyanochrysene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(1-ethynylnaphthalen-2-yl)benzonitrile → 1-cyanochrysene (68723-52-4) + chrysene-3-carbonitrile (36288-23-0)

Guidance literature:

With platinum(II) chloride; In toluene; at 150 ℃; for 1h; Overall yield = 31 %; Overall yield = 28 mg; regioselective reaction; Microwave irradiation; Sealed tube;

DOI:10.1016/j.tetlet.2016.12.004

Reference yield:

3-(1-hydroxy-1-((trimethylsilyl)ethynyl)-1,2-dihydronaphthalen-2-yl)benzonitrile → 1-cyanochrysene (68723-52-4) + chrysene-3-carbonitrile (36288-23-0)

Guidance literature:

Multi-step reaction with 3 steps

1: Amberlyst 15? ion exchange resin / dichloromethane / 1 h / 20 °C / Molecular sieve

2: tetrabutyl ammonium fluoride / tetrahydrofuran; dichloromethane / 0.5 h

3: platinum(II) chloride / toluene / 1 h / 150 °C / Microwave irradiation; Sealed tube

With tetrabutyl ammonium fluoride; platinum(II) chloride; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1016/j.tetlet.2016.12.004

Reference yield:

C22H19NSi → 1-cyanochrysene (68723-52-4) + chrysene-3-carbonitrile (36288-23-0)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran; dichloromethane / 0.5 h

2: platinum(II) chloride / toluene / 1 h / 150 °C / Microwave irradiation; Sealed tube

With tetrabutyl ammonium fluoride; platinum(II) chloride; In tetrahydrofuran; dichloromethane; toluene;

DOI:10.1016/j.tetlet.2016.12.004