(S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

Base Information

Chemical Name:(S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester
CAS No.:155711-40-3
Molecular Formula:C₅₈H₇₃Cl₆N₂O₁₆P
Molecular Weight:1297.91
Hs Code.:

(S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

Synonyms:

Suppliers and Price of (S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

There total 6 articles about (S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 155711-40-3
(S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 66 percent / TMU / CH₂Cl₂ / 24 h / Ambient temperature

2: 89 percent / pyridine-DMAP / CH₂Cl₂ / 16 h / Ambient temperature

3: 1.) 2)2>PF₆, 2.) I₂/water/pyridine / 1.) THF, 50 deg C, 2 h, 2.) THF, RT, 15 min

4: SOBr₂, DMF / CH₂Cl₂ / 2 h / 0 - 5 °C

5: HgBr₂ / CH₂Cl₂ / 24 h / Ambient temperature

With pyridine; dmap; sulfurous dibromide; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; water; iodine; N,N-dimethyl-formamide; tetramethylurea; mercury dibromide; In dichloromethane;
DOI:10.1248/cpb.41.1879

Reference yield:

: 134040-52-1
Allyl 2-deoxy-3-O-(2,2,2-trichloro-tert-butoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside

: 155711-40-3
(S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 66 percent / TMU / CH₂Cl₂ / 24 h / Ambient temperature

2: 89 percent / pyridine-DMAP / CH₂Cl₂ / 16 h / Ambient temperature

3: 1.) 2)2>PF₆, 2.) I₂/water/pyridine / 1.) THF, 50 deg C, 2 h, 2.) THF, RT, 15 min

4: SOBr₂, DMF / CH₂Cl₂ / 2 h / 0 - 5 °C

5: HgBr₂ / CH₂Cl₂ / 24 h / Ambient temperature

With pyridine; dmap; dibromo sulfoxide; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; water; iodine; N,N-dimethyl-formamide; tetramethylurea; mercury dibromide; In dichloromethane;
DOI:10.1248/cpb.41.1879

Reference yield:

: 155711-36-7
allyl 6-O-benzyloxymethyl-2-deoxy-3-O-(2,2,2-trichloro-tert-butoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside

: 155711-40-3
(S)-3-[(2R,3R,4R,5S,6R)-6-Benzyloxymethoxymethyl-5-(diphenoxy-phosphoryloxy)-4-(2,2,2-trichloro-1,1-dimethyl-ethoxycarbonyloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-tetrahydro-pyran-2-yloxy]-2-tetradecanoylamino-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / pyridine-DMAP / CH₂Cl₂ / 16 h / Ambient temperature

2: 1.) 2)2>PF₆, 2.) I₂/water/pyridine / 1.) THF, 50 deg C, 2 h, 2.) THF, RT, 15 min

3: SOBr₂, DMF / CH₂Cl₂ / 2 h / 0 - 5 °C

4: HgBr₂ / CH₂Cl₂ / 24 h / Ambient temperature

With pyridine; dmap; dibromo sulfoxide; (1,5-cyclooctadiene)[bis(methyldiphenylphosphine)]iridium(I) hexafluorophosphate; water; iodine; N,N-dimethyl-formamide; mercury dibromide; In dichloromethane;
DOI:10.1248/cpb.41.1879