2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl

Base Information

• Chemical Name: 2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl
• CAS No.: 1351866-66-4
• Molecular Formula: C₄₅H₃₄P₂S₂
• Molecular Weight: 700.844
• Mol file: 1351866-66-4.mol

Synonyms:

Chemical Property of 2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl

There total 3 articles about 2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-(+)-2-(diphenylphosphinyl)-2'-[(trifluoromethanesulfonyl)oxy]-1,1'-binaphthyl (132532-04-8,137769-34-7) → 2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl (1351866-66-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: phenylsilane / 110 °C / Inert atmosphere; Neat (no solvent)

2.1: 1,2-bis(diphenylphosphino)ethane nickel(II) chloride / N,N-dimethyl-formamide / 1 h / 100 °C / Glove box; Inert atmosphere

2.2: 103 h / 100 °C / Glove box; Inert atmosphere

2.3: 16 h / Inert atmosphere; Glove box

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; phenylsilane; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetasy.2011.09.007

Reference yield:

(R)-1,1'-Bi-2-naphthol (18531-94-7) → 2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl (1351866-66-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: pyridine / Inert atmosphere

2.1: palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane / Inert atmosphere

3.1: phenylsilane / 110 °C / Inert atmosphere; Neat (no solvent)

4.1: 1,2-bis(diphenylphosphino)ethane nickel(II) chloride / N,N-dimethyl-formamide / 1 h / 100 °C / Glove box; Inert atmosphere

4.2: 103 h / 100 °C / Glove box; Inert atmosphere

4.3: 16 h / Inert atmosphere; Glove box

With pyridine; 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; phenylsilane; palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetasy.2011.09.007

Reference yield:

(R)-(-)-1,1'-bi-2-naphthol triflate (128544-05-8,128575-34-8,141807-44-5,126613-06-7) → 2-((o-tolyl)(phenyl)phosphinothioyl)-2'-(diphenylphosphinothioyl)-1,10-binaphthyl (1351866-66-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane / Inert atmosphere

2.1: phenylsilane / 110 °C / Inert atmosphere; Neat (no solvent)

3.1: 1,2-bis(diphenylphosphino)ethane nickel(II) chloride / N,N-dimethyl-formamide / 1 h / 100 °C / Glove box; Inert atmosphere

3.2: 103 h / 100 °C / Glove box; Inert atmosphere

3.3: 16 h / Inert atmosphere; Glove box

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; phenylsilane; palladium diacetate; N-ethyl-N,N-diisopropylamine; 1,4-di(diphenylphosphino)-butane; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetasy.2011.09.007

upstream raw materials:

(R)-1,1'-Bi-2-naphthol

(R)-(+)-2-(diphenylphosphinyl)-2'-[(trifluoromethanesulfonyl)oxy]-1,1'-binaphthyl

(R)-(-)-1,1'-bi-2-naphthol triflate