3-AMINOCINNAMIC ACID ETHYL ESTER

Base Information

• Chemical Name: 3-AMINOCINNAMIC ACID ETHYL ESTER
• CAS No.: 125872-97-1
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Hs Code.: 2922498590
• Mol file: 125872-97-1.mol

Synonyms:ethyl (E)-3-(3-aminophenyl)acrylate;ethyl (2E)-3-(3-aminophenyl)prop-2-enoate;(E)-ethyl 3-(3-aminophenyl)acrylate;3-aminocinnamic acid ethyl ester;Ethyl m-aminocinnamate;ethyl (E)-3-aminocinnamate;ethyl (E)-meta-aminocinnamate;(E)-ethyl 3-aminophenylacrylate;2-Propenoic acid,3-(3-aminophenyl)-,ethyl ester,(E);ETHYL 3-(3-AMINOPHENYL)ACRYLATE;

Chemical Property of 3-AMINOCINNAMIC ACID ETHYL ESTER

Chemical Property:

• Melting Point: 48 °C
• Boiling Point: 348.3±25.0 °C(Predicted)
• PKA: 3.63±0.10(Predicted)
• PSA: 52.32000
• Density: 1.130±0.06 g/cm3(Predicted)
• LogP: 2.42630

Purity/Quality:

97% ^*data from raw suppliers

(E)-Ethyl3-aminocinnamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-AMINOCINNAMIC ACID ETHYL ESTER

There total 11 articles about 3-AMINOCINNAMIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(E)-ethyl 3-(3-nitrophenyl)acrylate (621-19-2) → ethyl (E)-3-(3-aminophenyl)acrylate (125872-97-1)

Guidance literature:

(E)-ethyl 3-(3-nitrophenyl)acrylate; With ethanol; water; tin(ll) chloride; at 60 ℃; for 2h;

With sodium hydrogencarbonate; Rochelle's salt; In water;

Reference yield: 98.0%

ethyl 3-(3-nitrophenyl)acrylate (5396-71-4) → ethyl (E)-3-(3-aminophenyl)acrylate (125872-97-1)

Guidance literature:

With tin(ll) chloride; In ethanol; for 12h; Reflux;

Reference yield: 78.0%

3-Iodoaniline (626-01-7) + ethyl acrylate (140-88-5,9003-32-1) → ethyl (E)-3-(3-aminophenyl)acrylate (125872-97-1)

Guidance literature:

With palladium diacetate; triethylamine; triphenylphosphine; In acetonitrile; Reflux;

DOI:10.1248/cpb.c17-00409

upstream raw materials:

(E)-ethyl 3-(3-nitrophenyl)acrylate

2-Bromoacetyl bromide

N-methylaniline

3-nitro-benzaldehyde

Downstream raw materials:

(E)-3-{3-[N-(quinoxalin-2-yl)amino]phenyl}acrylic acid ethyl ester

(E)-ethyl 3-(3-(6-nitroquinoxalin-3-ylamino)phenyl)acrylate

C₁₉H₁₆N₂O₅