1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane

Base Information

• Chemical Name: 1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane
• CAS No.: 870100-73-5
• Molecular Formula: C₄₂H₃₈F₆N₆O₇
• Molecular Weight: 852.79
• Mol file: 870100-73-5.mol

Synonyms:

Chemical Property of 1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane

There total 2 articles about 1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

1,5-bis(2,6-dimethylphenoxy)-3-oxapentane (92543-74-3) + 3-phenyl-1,2,4-triazin-5-one (54673-30-2) + trifluoroacetic anhydride (407-25-0) → 1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane (870100-73-5)

Guidance literature:

In trifluoroacetic acid; at 20 ℃; for 24h;

DOI:10.1007/s11172-005-0118-6

Reference yield:

2.6-dimethylphenol (576-26-1,25134-01-4) → 1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane (870100-73-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / dimethylformamide

1.2: 60 percent / dimethylformamide / 20 h / 110 - 115 °C

2.1: 63 percent / trifluoroacetic acid / 24 h / 20 °C

With sodium hydroxide; In N,N-dimethyl-formamide; trifluoroacetic acid;

DOI:10.1007/s11172-005-0118-6

Reference yield: 26.0%

1,5-bis[4-(5-oxo-3-phenyl-1-trifluoroacetyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane (870100-73-5) → 1,5-bis[4-(5-oxo-3-phenyl-1,4,5,6-tetrahydro-1,2,4-triazin-6-yl)-2,6-dimethylphenoxy]-3-oxapentane

Guidance literature:

With 3-azapentane-1,5-diamine; In methanol; for 5h; Heating;

DOI:10.1007/s11172-005-0118-6

upstream raw materials:

1,5-bis(2,6-dimethylphenoxy)-3-oxapentane

3-phenyl-1,2,4-triazin-5-one

trifluoroacetic anhydride

2.6-dimethylphenol