Technology Process of Acetic acid (1R,2S)-2-benzyloxy-1-[(Z)-4-(2-vinyl-[1,3]dioxolan-2-yl)-but-1-enyl]-heptyl ester
There total 8 articles about Acetic acid (1R,2S)-2-benzyloxy-1-[(Z)-4-(2-vinyl-[1,3]dioxolan-2-yl)-but-1-enyl]-heptyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1: CH(OMe)3, H(1+)
2: LiAlH4 / diethyl ether
3: 1) (COCl)2, DMSO, 2) Et3N
4: PPh3
5: 1) BuLi / 1) THF, -78 deg C, 2) THF
6: 1) (COCl)2, DMSO, 2) Et3N / 1) -78 deg C, 2) -78 to 0 deg C
7: 1) Zn(BH4)2, 2) i-BuMgCl, Cp2TiCl2, 3) pyridine
With
pyridine; bis(cyclopentadienyl)titanium dichloride; lithium aluminium tetrahydride; n-butyllithium; zinc(II) tetrahydroborate; oxalyl dichloride; 2-methylpropylmagnesium chloride; hydrogen cation; dimethyl sulfoxide; triethylamine; triphenylphosphine; trimethyl orthoformate;
In
diethyl ether;
DOI:10.1016/S0040-4039(00)76900-0
- Guidance literature:
-
Multi-step reaction with 6 steps
1: LiAlH4 / diethyl ether
2: 1) (COCl)2, DMSO, 2) Et3N
3: PPh3
4: 1) BuLi / 1) THF, -78 deg C, 2) THF
5: 1) (COCl)2, DMSO, 2) Et3N / 1) -78 deg C, 2) -78 to 0 deg C
6: 1) Zn(BH4)2, 2) i-BuMgCl, Cp2TiCl2, 3) pyridine
With
pyridine; bis(cyclopentadienyl)titanium dichloride; lithium aluminium tetrahydride; n-butyllithium; zinc(II) tetrahydroborate; oxalyl dichloride; 2-methylpropylmagnesium chloride; dimethyl sulfoxide; triethylamine; triphenylphosphine;
In
diethyl ether;
DOI:10.1016/S0040-4039(00)76900-0
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 1) (COCl)2, DMSO, 2) Et3N
2: CH(OMe)3, H(1+)
3: LiAlH4 / diethyl ether
4: 1) (COCl)2, DMSO, 2) Et3N
5: PPh3
6: 1) BuLi / 1) THF, -78 deg C, 2) THF
7: 1) (COCl)2, DMSO, 2) Et3N / 1) -78 deg C, 2) -78 to 0 deg C
8: 1) Zn(BH4)2, 2) i-BuMgCl, Cp2TiCl2, 3) pyridine
With
pyridine; bis(cyclopentadienyl)titanium dichloride; lithium aluminium tetrahydride; n-butyllithium; zinc(II) tetrahydroborate; oxalyl dichloride; 2-methylpropylmagnesium chloride; hydrogen cation; dimethyl sulfoxide; triethylamine; triphenylphosphine; trimethyl orthoformate;
In
diethyl ether;
DOI:10.1016/S0040-4039(00)76900-0
