4-(3,5-BIS-TRIMETHYLSILANYL-BENZOYLAMINO)-BENZOIC ACID METHYL ESTER

Base Information

Chemical Name:4-(3,5-BIS-TRIMETHYLSILANYL-BENZOYLAMINO)-BENZOIC ACID METHYL ESTER
CAS No.:125973-71-9
Molecular Formula:C21H29NO3Si2
Molecular Weight:399.63100
Hs Code.:
Mol file:125973-71-9.mol

Synonyms:Benzoic acid,4-[[3,5-bis(trimethylsilyl)benzoyl]amino]-,methyl ester;methyl 4-<<3,5-bis(trimethylsilyl)phenyl>carboxamido>benzoate;Methyl 4-(3,5-bis(trimethylsilyl)benzamido)benzoate;

Suppliers and Price of 4-(3,5-BIS-TRIMETHYLSILANYL-BENZOYLAMINO)-BENZOIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(3,5-BIS-TRIMETHYLSILANYL BENZOYLAMINO)BENZOIC ACID METHYL ESTER 95.00%
5MG
$ 497.57

Total 3 raw suppliers

Chemical Property of 4-(3,5-BIS-TRIMETHYLSILANYL-BENZOYLAMINO)-BENZOIC ACID METHYL ESTER

Chemical Property:

Boiling Point:394.0±42.0 °C(Predicted)
PKA:13.69±0.70(Predicted)
PSA：55.40000
Density:1.06±0.1 g/cm3(Predicted)
LogP:3.88890

Purity/Quality:

98%min ^*data from raw suppliers

4-(3,5-BIS-TRIMETHYLSILANYL BENZOYLAMINO)BENZOIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3,5-BIS-TRIMETHYLSILANYL-BENZOYLAMINO)-BENZOIC ACID METHYL ESTER

There total 5 articles about 4-(3,5-BIS-TRIMETHYLSILANYL-BENZOYLAMINO)-BENZOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 948552-39-4
3,5-Bis-trimethylsilanyl-benzoyl chloride

: 619-45-4
4-methoxycarbonyl aniline

: 125973-71-9
methyl 4-<<3,5-bis(trimethylsilyl)phenyl>carboxamido>benzoate

Guidance literature:: With triethylamine; In benzene;
DOI:10.1021/jm00167a024

Reference yield:

: 626-39-1
1,3,5-trisbromobenzene

: 125973-71-9
methyl 4-<<3,5-bis(trimethylsilyl)phenyl>carboxamido>benzoate

Guidance literature:: Multi-step reaction with 5 steps

1: 56 percent / Mg / tetrahydrofuran

2: 77 percent / AlCl₃ / CS₂ / 1 h / 0 °C

3: 33 percent / Ca(OCl)2, K₂CO₃, KOH / H₂O / 7.5 h / 110 °C

4: SOCl₂, CaCO₃ / benzene; dimethylformamide / 2 h / Ambient temperature

5: 36 percent / Et₃N / benzene

With potassium hydroxide; calcium hypochlorite; aluminium trichloride; thionyl chloride; potassium carbonate; magnesium; triethylamine; calcium carbonate; In tetrahydrofuran; carbon disulfide; water; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00167a024

Reference yield:

: 5624-60-2
1,3,5-tris(trimethylsilyl)benzene

: 125973-71-9
methyl 4-<<3,5-bis(trimethylsilyl)phenyl>carboxamido>benzoate

Guidance literature:: Multi-step reaction with 4 steps

1: 77 percent / AlCl₃ / CS₂ / 1 h / 0 °C

2: 33 percent / Ca(OCl)2, K₂CO₃, KOH / H₂O / 7.5 h / 110 °C

3: SOCl₂, CaCO₃ / benzene; dimethylformamide / 2 h / Ambient temperature

4: 36 percent / Et₃N / benzene

With potassium hydroxide; calcium hypochlorite; aluminium trichloride; thionyl chloride; potassium carbonate; triethylamine; calcium carbonate; In carbon disulfide; water; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00167a024