6-Methylpyridine-2-carbonyl chloride

Base Information

• Chemical Name: 6-Methylpyridine-2-carbonyl chloride
• CAS No.: 126125-54-0
• Molecular Formula: C7H6ClNO
• Molecular Weight: 155.584
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID40559027
• Wikidata: Q82441542
• Mol file: 126125-54-0.mol

Synonyms:6-methylpyridine-2-carbonyl chloride;126125-54-0;2-Pyridinecarbonyl chloride, 6-methyl- (9CI);6-Methylpicolinoyl chloride;2-PYRIDINECARBONYL CHLORIDE, 6-METHYL-;SCHEMBL512860;6-methylpicolinic acid chloride;DTXSID40559027;UXYLOINHCQMHHY-UHFFFAOYSA-N;MFCD11169667;6-methyl-pyridine-2-carbonyl chloride

Chemical Property of 6-Methylpyridine-2-carbonyl chloride

Chemical Property:

• PSA: 29.96000
• LogP: 1.76900
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 155.0137915
• Heavy Atom Count: 10
• Complexity: 138

Purity/Quality:

98%min ^*data from raw suppliers

6-Methylpyridine-2-carbonyl chloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC(=CC=C1)C(=O)Cl

Technology Process of 6-Methylpyridine-2-carbonyl chloride

There total 3 articles about 6-Methylpyridine-2-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-methyl-2-pyridinecarboxylic acid (934-60-1) → 6-methyl-pyridine-2-carbonyl chloride (126125-54-0)

Guidance literature:

With thionyl chloride; In dichloromethane; at 65 ℃; for 2h;

Reference yield:

6-methylpyridine-2-carboxylic acid hydrochlorid salt (87884-49-9) → 6-methyl-pyridine-2-carbonyl chloride (126125-54-0)

Guidance literature:

With thionyl chloride; for 2h; Heating;

DOI:10.1021/jm00368a005

Reference yield:

→ 6-methyl-pyridine-2-carbonyl chloride (126125-54-0)

Guidance literature:

With thionyl chloride;

upstream raw materials:

6-methyl-2-pyridinecarboxylic acid

6-methylpyridine-2-carboxylic acid hydrochlorid salt

Downstream raw materials:

6-methyl-N-(1H-tetrazol-5-yl)-2-pyridinecarboxamide

N,6-dimethyl-N-<4'-<4''-(methylamino)-3''-nitrobenzyl>-2'-nitrophenyl>pyridine-2-carboxamide

6-(N,N-Diethylcarbamoyl)-N-methyl-N-{4'-{4''-{N-methyl-N-[(6'''-methylpyridine-2'''-yl)carbonyl]amino}-3''-nitrobenzyl}-2'-nitrophenyl}pyridine-2-carboxamide

4-[1-benzo[1,3]dioxol-5-yl-5-(6-methyl-pyridin-2-yl)-1H-[1,2,4]triazol-3-yl]-benzonitrile