α,β-cis-benzamido-β-phenoxyproline tert-butyl amide

Base Information

• Chemical Name: α,β-cis-benzamido-β-phenoxyproline tert-butyl amide
• CAS No.: 83220-76-2
• Molecular Formula: C₂₂H₂₆N₂O₃
• Molecular Weight: 366.46
• Mol file: 83220-76-2.mol

Synonyms:

Chemical Property of α,β-cis-benzamido-β-phenoxyproline tert-butyl amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α,β-cis-benzamido-β-phenoxyproline tert-butyl amide

There total 6 articles about α,β-cis-benzamido-β-phenoxyproline tert-butyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-phenoxypyrrolidine (21767-14-6) → α,β-trans-benzamido-β-phenoxyproline tert-butyl amide (83220-76-2,83220-78-4)

Guidance literature:

Multi-step reaction with 3 steps

1: tert-butyl hypochlorite / 0 °C

2: sodium methoxide

3: methanol

With tert-butylhypochlorite; sodium methylate; In methanol;

DOI:10.1021/ja00385a080

Reference yield:

3-phenoxypyrrolidine (21767-14-6) → α,β-cis-benzamido-β-phenoxyproline tert-butyl amide (83220-76-2,83220-78-4)

Guidance literature:

Multi-step reaction with 3 steps

1: tert-butyl hypochlorite / 0 °C

2: sodium methoxide

3: methanol

With tert-butylhypochlorite; sodium methylate; In methanol;

DOI:10.1021/ja00385a080

Reference yield:

1-Chloro-3-phenoxy-pyrrolidine (83220-82-0) → α,β-trans-benzamido-β-phenoxyproline tert-butyl amide (83220-76-2,83220-78-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium methoxide

2: methanol

With sodium methylate; In methanol;

DOI:10.1021/ja00385a080

upstream raw materials:

tert-butylisonitrile

4-Phenoxy-3,4-dihydro-2H-pyrrole

benzoic acid

3-phenoxypyrrolidine