pentafluorophenyl 12-thioacetyldodecanoate

Base Information

• Chemical Name: pentafluorophenyl 12-thioacetyldodecanoate
• CAS No.: 1448789-81-8
• Molecular Formula: C₂₀H₂₅F₅O₃S
• Molecular Weight: 440.475
• Mol file: 1448789-81-8.mol

Synonyms:

Chemical Property of pentafluorophenyl 12-thioacetyldodecanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pentafluorophenyl 12-thioacetyldodecanoate

There total 2 articles about pentafluorophenyl 12-thioacetyldodecanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

2,3,4,5,6-pentafluorophenol (771-61-9) + 12-acetylsulfanildodecanoic acid (352439-40-8) → pentafluorophenyl 12-thioacetyldodecanoate (1448789-81-8)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ja406688a

Reference yield:

12-bromododecanoic acid (73367-80-3) → pentafluorophenyl 12-thioacetyldodecanoate (1448789-81-8)

Guidance literature:

Multi-step reaction with 2 steps

1: acetone / 48 h / 55 °C

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 12 h / 20 °C / Inert atmosphere

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; acetone;

DOI:10.1021/ja406688a

Reference yield:

gold + pentafluorophenyl 12-thioacetyldodecanoate (1448789-81-8) → 70C20H25F5O3S*Au180

Guidance literature:

In isopropyl alcohol;

DOI:10.1021/ja406688a

upstream raw materials:

12-bromododecanoic acid

2,3,4,5,6-pentafluorophenol

12-acetylsulfanildodecanoic acid