2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin

Base Information

• Chemical Name: 2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin
• CAS No.: 156760-98-4
• Molecular Formula: C₁₅H₁₅N₃S
• Molecular Weight: 269.37
• Mol file: 156760-98-4.mol

Synonyms:

Chemical Property of 2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin

There total 2 articles about 2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1,2,3,4-tetrahydrophthalazine hydrochloride (60789-87-9) + phenyl isothiocyanate (103-72-0) → 2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin (156760-98-4)

Guidance literature:

With sodium hydroxide; 1.) water, 2.) water, acetone, 140 min, RT;

Reference yield:

PHTHALAZINE (253-52-1) → 2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin (156760-98-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / 1.) 7percent Na/Hg, 2.) HCl / H₂O / 0.33 h / 1.) 20 min, 2.) pH = 3

2: 80 percent / 1.) 0.2M NaOH / 1.) water, 2.) water, acetone, 140 min, RT

With hydrogenchloride; sodium hydroxide; sodium amalgam; In water;

Reference yield: 60.0%

thiophosgene (463-71-8) + 2-<(N-Phenyl)thiocarbamoyl>-1,2,3,4-tetrahydrophthalazin (156760-98-4) → 3-Phenylimino-1-thioxo-5,10-dihydro-<1,3,4>thiadiazolo<3,4-b>phthalazin

Guidance literature:

With sodium carbonate; In chloroform; for 2h; Ambient temperature;

upstream raw materials:

1,2,3,4-tetrahydrophthalazine hydrochloride

phenyl isothiocyanate

PHTHALAZINE