Chemical Property of Bromozinc(1+);2-methanidylpropane
Chemical Property:
- Flash Point:1 °F
- PSA：0.00000
- Density:0.943 g/mL at 25oC
- LogP:2.45310
- Storage Temp.:2-8°C
- Sensitive.:Air Sensitive
- Water Solubility.:Reacts with water.
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:0
- Exact Mass:199.91790
- Heavy Atom Count:6
- Complexity:9.5
- Purity/Quality:
-
98%,99%, *data from raw suppliers
Isobutylzinc bromide solution
0.5 M in THF *data from reagent suppliers
Safty Information:
- Pictogram(s):
F,
Xn
- Hazard Codes:F,Xn
- Statements:
14-19-22-36/37/38-40-36/37-14/15-11
- Safety Statements:
16-23-26-36-43-36/37
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CC(C)[CH2-].[Zn+]Br
-
Uses
Isobutylzinc bromide is an organozinc compound, which can be used as a reagent in the palladium-catalyzed Negishi cross-coupling reaction to construct a carbon-carbon bond by reacting with aryl or heteroaryl halides . It is also used to prepare regioselective unsaturated ketones by reacting with tert-butyl isocyanide via an allylic carbonylative coupling reaction in the presence of a nickel catalyst.
