C₅₁H₄₉N₃O₁₃P₂

Base Information

• Chemical Name: C₅₁H₄₉N₃O₁₃P₂
• CAS No.: 1346525-96-9
• Molecular Formula: C₅₁H₄₉N₃O₁₃P₂
• Molecular Weight: 973.91
• Mol file: 1346525-96-9.mol

Synonyms:

Chemical Property of C₅₁H₄₉N₃O₁₃P₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₅₁H₄₉N₃O₁₃P₂

There total 3 articles about C₅₁H₄₉N₃O₁₃P₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C24H23N3O8 (1346525-93-6) → C51H49N3O13P2 (1346525-96-9)

Guidance literature:

Multi-step reaction with 2 steps

1: bis-triphenylphosphine-palladium(II) chloride; 4-nitro-phenol; tri-n-butyl-tin hydride / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 2 h / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; 4-nitro-phenol; tri-n-butyl-tin hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane;

DOI:10.1021/ja207587x

Reference yield:

1,4,5,8-naphthalenetetracarboxylic dianhydride (81-30-1) → C51H49N3O13P2 (1346525-96-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / N,N-dimethyl-formamide / 0.08 h / 140 °C / Microwave irradiation; Inert atmosphere

1.2: 0.08 h / 140 °C / Inert atmosphere

2.1: bis-triphenylphosphine-palladium(II) chloride; 4-nitro-phenol; tri-n-butyl-tin hydride / dichloromethane / 2 h / 20 °C / Inert atmosphere

3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 2 h / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; 4-nitro-phenol; tri-n-butyl-tin hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja207587x

Reference yield:

C20H19N3O6 + 3,3-bis(dibenzyloxyphosphoryl)propanoic acid (183383-58-6) → C51H49N3O13P2 (1346525-96-9)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; for 2h; Inert atmosphere;

DOI:10.1021/ja207587x

upstream raw materials:

C₂₄H₂₃N₃O₈

3,3-bis(dibenzyloxyphosphoryl)propanoic acid

1,4,5,8-naphthalenetetracarboxylic dianhydride